Acetylcholine and Acetylcholine Receptors 2.0

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 167

Special Issue Editor


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Guest Editor
Neurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Interests: acetylcholine; nicotine; hippocampus; synaptic plasticity; theta oscillation
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Special Issue Information

Dear Colleagues,

Acetylcholine transmission in the central nervous system plays an important role in higher brain cognitive functions, including learning and memory. The dysfunction of cholinergic transmission is related to many neurological disorders, including Alzheimer’s disease and schizophrenia. There are two major acetylcholine receptors, namely, the metabotropic muscarinic receptor and ionic nicotinic receptor. Within each group, there are also many subtypes. These receptor subtypes have different expression patterns throughout the brain subregions and neuronal subpopulations and will thus result in various outcomes in regulating brain activities. In addition, the outcome also depends on other ongoing brain activities. One of the major challenges is thus to understand how individual receptor subtype and neuronal subpopulation work with each other to achieve the desired results in regulating brain functions.

Dr. Zhenglin Gu
Guest Editor

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Keywords

  • acetylcholine
  • muscarinic
  • nicotinic
  • learning and memory
  • synaptic transmission
  • neuromodulator

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