Animal and Cellular Models of Alzheimer’s Disease, 2nd Edition

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 80

Special Issue Editors

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Guest Editor
Department of Cell Biology, Genetics and Physiology, Faculty of Sciences, University of Malaga, Malaga, Spain
Interests: Alzheimer's disease; multiple sclerosis, human pluripotent stem cells; glial cells
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Guest Editor
Group of Stem Cell Models for Studies of Neurodegenerative Diseases, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1870 Frederiksberg, Denmark
Interests: induced pluripotent stem cells; cellular disease models; CRISPR; neurodegeneration and models of neurodegeneration
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
1. Departamento Biologia Celular, Genetica y Fisiologia, Instituto de Investigacion Biomedica de Malaga-IBIMA, Facultad de Ciencias, Universidad de Málaga, Málaga, Spain
2. Centro de Investigación Biomedica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
Interests: Alzheimer's disease; animal models; diabetes; obesity; insulin resistance; tau; cognitive impairments; inflammation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Alzheimer’s disease (AD) is a neurodegenerative condition with no cure. In the last three decades, important efforts have been made in the development and characterization of animal models of the disease, with the aim to translate the discoveries made toward the clinical setting. Nonetheless, to date, there is no effective treatment able to counteract the progression of AD. This points toward an urgent need to develop new and more reliable models of the disease.

This Special Issue is focused on manuscripts describing and/or characterizing new animal and cellular models for AD. Special attention will be given to those works employing humanized animal models as well as studies based on human pluripotent stem cell technologies, strategies that should govern AD research in the coming years.

This Special Issue is open to basic and clinical research or multidisciplinary approaches and will also cover original articles and reviews on the following topics:

  • Characterization of new models relevant for AD;
  • Studies performed employing new cellular and animal models focused on AD;
  • Studies employing human pluripotent stem-cell-derived neuronal and glial cells for AD or other neurodegenerative conditions;
  • Evaluation of candidate therapies;
  • Modeling of Alzheimer’s disease or other neurodegenerative conditions.

Dr. Juan A. García León
Dr. Kristine Freude
Dr. David Baglietto-Vargas
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Alzheimer’s disease
  • cellular models
  • animal models
  • humanized models
  • human pluripotent stem cells
  • drug evaluation
  • neurodegenerative diseases
  • glial cells

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Published Papers

This special issue is now open for submission.
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