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Topical Collection "Extracellular Vesicles: From Biomarkers to Therapeutic Tools"
A topical collection in Biology (ISSN 2079-7737). This collection belongs to the section "Cell Biology".Viewed by 35583
Interests: acute myeloid leukemia (AML); chronic myeloid leukemia (CML); familiarity and genetic predisposition in hematologic malignancies; next generation sequencing (NGS); digital PCR (dPCR); exosomes and extracellular vesicles; liquid biopsy; zebrafish model; mesenchymal and hematopoietic stem cells (MSCs and HSCs); regenerative medicine; circulating endothelial cells (CEC)
Special Issues, Collections and Topics in MDPI journals
Interests: myocardial infarction (MI); drug cardiotoxicity; amniotic fluid stem cells (AFS); mesenchymal stem cells (MSC); cardiac progenitor cells (CPC); regenerative medicine; paracrine therapy; exosome and extracellular vesicles; biomarkers
Topical Collection Information
Intercellular communication is an essential hallmark of multicellular organisms and can be mediated through direct cell–cell contact or transfer of secreted molecules. In the last two decades, a third mechanism for intercellular communication has emerged that involves intercellular transfer of extracellular vesicles (EVs).
EVs are membranous vesicles of 30–5000 nm in size. Based on their dimension and biogenesis, EVs can be divided into different categories, such as microvesicles, apoptotic bodies, ectosomes, and exosomes. It has already been demonstrated that changing in protein, expressed on surfaces or content in these vesicles, may reflect the status of producing cells. For this reason, EVs, and exosomes in particular, are considered ideal biomarkers in several types of disease from cancer diagnosis to heart rejection. Furthermore, extracellular vesicles can be carriers of cytoprotective or cytotoxic factors and used as a therapeutic tool applied from regenerative medicine to target cancer therapy.
This Topical Collection focuses on recent findings pertaining to EV in different areas from biomarkers to therapeutic application. We warmly welcome experts to submit previously unpublished original scientific research with novel findings and reviews with a comprehensive overview of EVs.
Dr. Simona Bernardi
Dr. Carolina Balbi
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- extracellular vesicles
- drug carrier
- solid and hematologic malignancies
- extracellular vesicle engineering
- extracellular vesicle isolation
- extracellular vesicle characterization
- regenerative medicine
- liquid biopsy
- cell–cell communication
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