Microbes-on-a-Chip: Manipulation, Analysis, Detection and Growth of Pathogenic Microorganisms in Micro/Nanosystems
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanotechnology Applications in Bioengineering".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 603
Special Issue Editors
Interests: biomaterials; microfluidics; organ-on-chip; nanotechnology; cell separation; microbiology
Special Issues, Collections and Topics in MDPI journals
Interests: microfluidics; microdevices; chemical sensors; hemodynamics; microfabrication; additive manufacturing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
In the last decades, micro- and nano-scaled devices have reshaped the fundamental and applied research in the area of diagnostics, drug development, analytical methods, and chemical sensing. Recently, the use of micro-/nano-systems has been extended to the study of microorganisms for point-of-care and lab-based diagnostics, as well as for preclinical drug research. These platforms are used for analyzing microbes inside a microenvironment, from a single-cell scale to cells population with precise control of the chemicals, gases, temperature, nutrients supplies, and removal of wastes. Different microfluidic technologies have been proposed for microbe manipulation and analysis (separation, trapping, detection, biofilm formation, gradient generator for antimicrobial susceptibility testing etc.), owing to its highly precise control and lysis-free operation, portability, reduced sample/reagents, lower costs, ease of operation and automation. These devices can be easily employed for the analysis of multiple parameters on a single device. In addition, a variety of nanodevices and nanoparticles have been developed for the rapid capture and removal of pathogens (bacteria, viruses, etc.) from the contaminated source and biospecimen.
Owing to the high potential and growing interest in this area, this Special Issue seeks to showcase research papers, short communications, and review articles that focus on the use of micro-/nano-systems for the study and analysis of microbes, with particular interest in microfluidic platforms for the separation of microbes from water or blood, biofilm formation, and innovative microfabrication technologies.
Keywords
- microfluidics
- lab-on-a-chip
- point-of-care
- diagnostic
- cell separation
- sample preparation
- nanoparticles
- microparticles
- microscale bioengineering
- cell encapsulation
- biofilms
