Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.046
Journals
Bioengineering
Special Issues
Biological Production of Value-Added Products
share announcement

Special Issue "Biological Production of Value-Added Products"

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biochemical Engineering".

Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 2941

Special Issue Editors

Dr. Victor Ujor

E-Mail Website
Guest Editor
Department of Food Science, University of Wisconsin–Madison, Madison, WI 53706, USA
Interests: synthetic biology/metabolic engineering; fermentation science; bioconversion of food and agricultural wastes to fuels and biochemicals; bioprocess design
Dr. Christopher Okonkwo

E-Mail Website
Guest Editor
Biotechnology Program, College of Science, The Roux Institute, Northeastern University, Portland, ME, USA
Interests: application of synthetic biology; metabolic engineering; environmental biology; bioprocess design, and bioinformatics tools to enhance the production of biofuels and bio-derived chemicals from agricultural wastes/residues

Special Issue Information

Dear Colleagues,

In light of the growing impact of climate change, it has become imperative to source bulk and specialty chemicals, as well as packaging materials from renewable resources not based on fossil fuels. It is important that renewable strategies are designed to reduce net emissions of greenhouse gases (GHGs) and, where possible, to sequester GHGs from the atmosphere, consume less water (or recover reusable water from effluents wherever possible), produce more environmentally benign wastes, and incorporate measures for efficient waste management. Moreover, renewably sourced products need to compete favorably with their fossil-derived counterparts in economic terms. Thus, among other challenges, this calls for adroit measures to convert cheap feedstock (including waste) to value-added products, increase yield and productivity, eliminate expensive additives from production systems, and minimize the cost of downstream processing. Therefore, the aim of this Special Issue is to highlight the breadth of ongoing efforts to efficiently convert assorted feedstock to value-added products. This includes the deployment of synthetic biology, metabolic perturbations, and bioprocess design as tools to increase yield and productivity. Further, the Special Issue shines light on efforts in the area of waste valorization, the bioconversion of CO2 to value-added products, and novel feats in downstream processing.

Dr. Victor Ujor
Dr. Christopher Okonkwo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomanufacturing
  • bioconversion
  • bioproduction
  • renewable products
  • downstream processing
  • synthetic biology
  • bioengineering
  • metabolic engineering
  • fermentation

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

get_app
Article
Endochitinase and Chitobiosidase Production by Marine Aeromonas caviae CHZ306: Establishment of Nitrogen Supplementation
by
Flavio Cardozo
,
Valker Feitosa
,
Omar Pillaca-Pullo
and
Adalberto Pessoa
Bioengineering 2023, 10(4), 431; https://doi.org/10.3390/bioengineering10040431 - 29 Mar 2023
Viewed by 626
Abstract
Aeromonas caviae CHZ306, a marine-derived bacterium isolated from zooplankton, can use chitin (a polymer of a β-(1,4)-linked N-acetyl-D-glucosamine) as a carbon source. The chitin is hydrolyzed by chitinolytic enzymes, namely endochitinases and exochitinases (chitobiosidase and N-acetyl-glucosaminidase). Indeed, the chitinolytic pathway is [...] Read more.
Aeromonas caviae CHZ306, a marine-derived bacterium isolated from zooplankton, can use chitin (a polymer of a β-(1,4)-linked N-acetyl-D-glucosamine) as a carbon source. The chitin is hydrolyzed by chitinolytic enzymes, namely endochitinases and exochitinases (chitobiosidase and N-acetyl-glucosaminidase). Indeed, the chitinolytic pathway is initiated by the coexpression of the enzymes endochitinase (EnCh) and chitobiosidase (ChB); however, few studies, including biotechnological production of these enzymes, have been reported, although chitosaccharide are helpful in several industries, such as cosmetics. This study demonstrates the potential to maximize the simultaneous EnCh and ChB production by nitrogen supplementation on culture media. Twelve different nitrogen supplementation sources (inorganic and organic) previously analyzed in elemental composition (carbon and nitrogen) were tested and evaluated in the Erlenmeyer flask culture of A. caviae CHZ306 for EnCh and ChB expression. None of the nutrients inhibited bacterial growth, and the maximum activity in both EnCh and ChB was observed at 12 h, using corn-steep solids and peptone A. Corn-steep solids and peptone A were then combined at three ratios (1:1, 1:2, and 2:1) to maximize the production. The high activities for EnCh (30.1 U.L−1) and ChB (21.3 U.L−1) were obtained with 2:1 corn-steep solids and peptone A, corresponding to more than 5- and 3-fold enhancement, respectively, compared to the control condition. Full article
(This article belongs to the Special Issue Biological Production of Value-Added Products)
►▼ Show Figures

Graphical abstract

get_app
Article
A Novel Strategy to Enhance Antioxidant Content in Saccharomyces Cerevisiae Based on Oxygen Pressure
by
Na Cui
,
Patrick Perré
,
Emilie Michiels
and
Victor Pozzobon
Bioengineering 2023, 10(2), 246; https://doi.org/10.3390/bioengineering10020246 - 13 Feb 2023
Viewed by 716
Abstract
Antioxidant foods represent a potent lever to improve diets while creating value. Yet, their cultivation is often tied to a specific area and climate, limiting availability and increasing market cost. Therefore, microorganism-based antioxidant production emerges as a promising technology to solve these problems. [...] Read more.
Antioxidant foods represent a potent lever to improve diets while creating value. Yet, their cultivation is often tied to a specific area and climate, limiting availability and increasing market cost. Therefore, microorganism-based antioxidant production emerges as a promising technology to solve these problems. In this view, a novel process was investigated for antioxidant accumulation in yeast culture. S. cerevisiae cells were exposed to various hyperbaric air conditions from 1 to 9 bar (A). Yeast cultures exhibited an increased reactive oxygen species content, which induced oxidative defense expression. After a few hours, reactive oxygen species levels decreased while antioxidant contents remained high, leading to a net increase in antioxidant power. At 6 bar (A), yeast achieved the highest net antioxidant power (phenolics content +48.3 ± 18.6 %, reducing power +120 ± 11.4 %) with an acceptable growth rate (0.27 h−1). Regarding time evolution, a 2 h exposure seems to be the optimum: cells have the lowest reactive oxygen species level while their antioxidant power is increased. From a biotechnological perspective, this finding highlights air pressure as an antioxidant-manipulating stress strategy. Moreover, the proposed process led to a patent that could potentially reduce energy and chemical consumption in such antioxidant accumulation processes. Full article
(This article belongs to the Special Issue Biological Production of Value-Added Products)
►▼ Show Figures

Graphical abstract

get_app
Article
Dairy and Wine Industry Effluents as Alternative Media for the Production of Bacillus-Based Biocontrol Agents
by
Selena Dmitrović
,
Ivana Pajčin
,
Vanja Vlajkov
,
Mila Grahovac
,
Aleksandar Jokić
and
Jovana Grahovac
Bioengineering 2022, 9(11), 663; https://doi.org/10.3390/bioengineering9110663 - 08 Nov 2022
Cited by 5 | Viewed by 1182
Abstract
Food industry effluents represent one of the major concerns when it comes to environmental impact; hence, their valorization through different chemical and biological routes has been suggested as a possible solution. The vast amount of organic and inorganic nutrients present in food industry [...] Read more.
Food industry effluents represent one of the major concerns when it comes to environmental impact; hence, their valorization through different chemical and biological routes has been suggested as a possible solution. The vast amount of organic and inorganic nutrients present in food industry effluents makes them suitable substrates for microbial growth. This study suggests two valorization routes for whey as dairy industry effluent and flotation wastewater from the wine industry through microbial conversion to biocontrol agents as value-added products. Cultivations of the biocontrol strain Bacillus sp. BioSol021 were performed in a 16 L bioreactor to monitor the bioprocess course and investigate bioprocess kinetics in terms of microbial growth, sugar substrate consumption and surfactin synthesis, as an antimicrobial lipopeptide. The produced biocontrol agents showed high levels of biocontrol activity against mycotoxigenic strains of Aspergillus flavus, followed by a significant reduction of sugar load of the investigated effluents by the producing microorganisms. With proven high potential of whey and winery flotation wastewater to be used as substrates for microbial growth, this study provides grounds for further optimization of the suggested valorization routes, mostly in terms of bioprocess conditions to achieve maximal techno-economical feasibility, energy saving and maximal reduction of effluents’ organic and inorganic burden. Full article
(This article belongs to the Special Issue Biological Production of Value-Added Products)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop