Special Issue "From Yeast to Biotechnology"
A special issue of Bioengineering (ISSN 2306-5354).
Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 47406
Interests: synthetic biology; directed evolution; metabolic engineering; sustainable green processes; yeast
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Yeast is regarded as a versatile tool for biotechnological purposes. For thousands of years, yeasts have been exploited by mankind for the production of food and beverages. Their metabolic versatility, robustness under fermentation conditions, generally recognized as safe (GRAS) status, ease of culture, and the availability of biomolecular tools have turned yeasts into one of the main workhorses in biotechnology. Recent advances in genomics, metabolic engineering, and synthetic biology have enabled the engineering of yeasts to function as microfactories for the production of relevant compounds such as pharmaceuticals, biofuels, fine chemicals, or proteins. Yeasts also have a great potential in molecular biology as a biomolecular toolbox. Among the various yeast species, Saccharomyces cerevisiae stands out for its high fidelity and high frequency of homologous DNA recombination, which has been successfully exploited in the synthesis of large DNA fragments (as whole genomes) and engineering of enzymes by directed evolution through so-called in vivo DNA shuffling.
Although S. cerevisiae is the best genetically and biologically characterized yeast and that most widely used in industrial applications, new players are rapidly emerging, such as Pichia pastoris, Hansenula polymorpha, Yarrowia lipolytica, and Kluyveromyces marxianus, to name but a few.
For this Special Issue “From Yeast to Biotechnology” we invite authors to submit articles covering all aspects of this theme, including, but not limited to, yeast engineering for high-value compound production, yeast genome engineering, computational design/modeling/analysis applied to yeast biotechnology, methods to characterize yeast, yeast as biomolecular toolbox, yeast biosensors, and/or yeast industrial fermentation processes.
Dr. Eva Garcia Ruiz
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.