Special Issue "Recent Advances and Novel Strategies against Inflammatory Diseases: Targeted Drug Discovery and Delivery"
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanotechnology Applications in Bioengineering".
Deadline for manuscript submissions: 24 December 2023 | Viewed by 930
Special Issue Editors
Interests: inflammation therapy; drug delivery; nanomaterials; macromolecular carriers
Interests: antibacterial therapy; biomaterials; cancer therapy; drug delivery and nanomaterials
Interests: biomaterials; nanoparticles; drug delivery; cancer therapy; neurological disorder treatment
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Inflammation is known to be a protective immune response for maintaining tissue homeostasis by eliminating harmful stimuli, including damaged cells, irritants, pathogens, and sterile lesions. Cell interactions in the innate immune system, adaptive immune system, and inflammatory mediators are involved in various types of inflammatory diseases, including acute disorders such as acute liver injury and acute lung injury, as well as chronic disorders such as autoimmune and cancer. These inflammatory diseases pose a crucial threat to human life and health; therefore, it is urgent that specific, quick, and effective prevention, diagnosis, and cures are explored for these inflammatory diseases.
This research topic welcomes submissions of original research articles and reviews that are related to novel drugs and drug delivery systems, including newly active compounds, nano drugs, vaccines, biosensors, nano-delivery systems, micro-delivery systems, macromolecular carrier drug conjugates, prodrugs, and biological therapies for the diagnosis, prevention, and treatment of inflammatory diseases. Potential subtopics include, but are not limited to, the following areas:
- Newly discovered pathogenesis and targets of inflammatory diseases;
- Nanomaterial-assisted or biomaterial-assisted drug delivery strategies;
- Therapeutic nanomaterials for inflammatory diseases;
- Novel nanotherapeutic strategies;
- Diagnostic uses of nanomaterials or biomaterials;
- Vaccines and biosensors for inflammatory diseases;
- Newly active compounds, micro/nanocrystal drugs, macromolecular carrier drug conjugates, and prodrugs against inflammatory diseases;
- Pharmacokinetics of drugs and prodrugs for inflammatory diseases;
- Discussing the latest progress in inflammatory diseases;
- Exploring the potential of biological therapies for inflammatory diseases;
- Discover or construct new drug carriers to treat inflammatory diseases.
Prof. Dr. Zhi-Xiang Yuan
Dr. Qiang Peng
Dr. Tianqing (Michelle) Liu
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- inflammation
- immunity
- anti-inflammatory drugs
- delivery systems
- nanomaterials
Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Potential of nanomaterials-based photodynamic therapy in antibacterial treatment
Authors: Yujie Gao (the 1st author), Jv Li, Yejiao Luo, Hua Lin, Qiang Peng, Renguo Gong (the corresponding author)
Affiliation: West China School/Hospital of Stomatology, Sichuan University, Chengdu, China
Abstract: Microbial infections have been a persistent health problem for humans, especially with the emergence of drug-resistant bacteria. The failure of traditional antibiotic therapies has led researchers to explore alternative strategies. Photodynamic therapy (PDT) is a promising alternative that generates reactive oxygen species (ROS) to induce bacterial oxidative stress and has the potential for cyclic treatment without causing the development of new drug resistance mechanisms. The efficacy of PDT largely depends on the choice of photosensitizers. At present, various nanomaterials are constructed to be used as drug carriers or photosensitizers to improve the efficacy of PDT in antibacterial field. In this article, we provide a comprehensive review of four main ROS generated in the process of PDT, and summarize their corresponding antibacterial mechanisms. Furthermore, we highlight typical types of nanomaterials used as photosensitizers or carriers in PDT. We analyze the current challenges in the development of nanomaterial-based PDT for antibacterial therapy, and discuss potential strategies for optimizing their applications
