Quantitative MR Imaging for the Evaluation of Neurovascular Disease

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 94

Special Issue Editors

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Guest Editor
Department of Radiology, The University of Chicago, Chicago, IL, USA
Interests: imaging; magnetic resonance; physics; stroke; cerebrovascular; vascular disease

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Guest Editor
Department of Radiology (M.C.H.), University of Chicago, Chicago, IL, USA
Interests: diagnostic and interventional neuroradiology; neurointerventional surgery

Special Issue Information

Dear Colleagues,

Neurovascular disease is one of the leading causes of death and disability worldwide. A continuing series of technical innovations overcoming initial technical challenges since the 1980s has resulted in a plethora of magnetic resonance neurovascular imaging pulse sequences and post-processing algorithms targeting the vessel lumen (TOF-MRA, CE-MRA, TR-MRA), vessel wall (3D TSE BB), cerebral perfusion (ASL, DSC, IVIM), and permeability (DCE). MRI images are traditionally presented as proportional or “weighted” images in which the signal intensity depends not only on the specific type of pulse sequence used but also sequence parameters such at the TR, TE and flip angle. An increasing number of quantitative acquisitions have been derived and commercialized to generate absolute measurements of the contribution to signal with parameters such as T1, T2, susceptibility, phase shift, and enhancement to generate quantitative pathophysiological properties such as velocity, flow, permeability and even tissue perfusion (cerebral blood flow (CBF)). Accurate quantification has the advantages of truly objective cross-sectional comparisons of normative and pathologic values as well as longitudinal assessment of a single patient in response to compensatory mechanisms. For example, longitudinal quantification of cerebral blood flow (qCBF) can enhance the clinical evaluation of chronic cerebrovascular ischemia progression versus response to treatment in patients with intracranial atherosclerotic disease and helps ensure that individual patients are triaged to receive the appropriate treatment in the case of ischemic stroke.

The goal of this Special Issue, entitled “Quantitative MR Imaging for the Evaluation of Neurovascular Disease”, is to highlight recent work in the development, validation and application of quantitative MRI. We welcome original research papers, communications, and review articles that reflect recent technical developments of quantitative MRI in the evaluation of neurovascular disease.

Prof. Dr. Timothy J. Carroll
Prof. Dr. Michael C Hurley
Guest Editors

Manuscript Submission Information

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  • quantification
  • neurovascular
  • stroke
  • atherosclerosis
  • aneurysm
  • chronic
  • intervention

Published Papers

This special issue is now open for submission.
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