Cell Mechanobiology in Health and Disease

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 21 October 2024 | Viewed by 67

Special Issue Editor

E-Mail Website
Guest Editor
Department of Biomedical Engineering, Michigan Technological University, Houghton, MI, USA
Interests: mechanobiology; ECM stiffness sensing; focal adhesion; cytoskeletal dynamics; Ehlers–Danlos syndrome; cancer mechanobiology

Special Issue Information

Dear Colleagues,

I am thrilled to announce that we are preparing a Special Issue dedicated to exploring the fascinating realm of Cell Mechanobiology in Health and Disease, and I am honored to serve as the Guest Editor. The dynamic interplay between cellular mechanics and biological functions has emerged as a critical determinant in understanding the complexities of health and the pathogenesis of diseases. This Special Issue aims to highlight cutting-edge research and innovative reviews that shed light on the mechanobiological principles underlying cellular processes and their implications for disease progression, diagnosis, and therapy.

Cell mechanobiology is pivotal for deciphering the intricacies of cellular responses to their mechanical environment, impacting areas from tissue regeneration and cancer metastasis to the progression of cardiovascular and musculoskeletal diseases. Insights into how cells sense, respond to, and are influenced by mechanical stimuli open new avenues for therapeutic intervention and diagnostic advancements. We are particularly interested in submissions that explore the role of mechanotransduction in disease development, the application of mechanobiological principles in the design of biomaterials and tissue engineering, and novel methodologies for investigating cellular mechanics in health and disease contexts.

Contributions may range from original research articles that provide novel insights into cell mechanobiology's role in health and disease to comprehensive reviews that summarize current knowledge and future directions in the field. We welcome studies that employ interdisciplinary approaches, combining techniques from biology, physics, engineering, and computational sciences, to unravel the complex interactions at play.

This Special Issue represents an exciting opportunity for researchers in the field of cell mechanobiology to showcase their work to a broad audience and to foster collaborations that bridge disciplinary divides. We believe that your contribution could be a cornerstone in advancing our understanding of cell mechanobiology and its potential to revolutionize therapeutic strategies for a wide array of diseases.

We look forward to your participation in this endeavor to illuminate the intricate dance between cellular mechanics and biological outcomes, propelling forward advances in science and medicine.

Dr. Sangyoon Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • mechanobiology
  • fibroblasts
  • immune cells
  • stem cells
  • cancer cells
  • connective tissue disorder
  • extracellular matrix
  • shear stress sensing

Published Papers

This special issue is now open for submission.
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