Implantable Medical Devices: 2nd Edition

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1030

Special Issue Editor


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Guest Editor
Department of Mechanical Engineering, University of Kansas, Lawrence, KS 66045, USA
Interests: orthopaedic biomechanics; biomaterials; medical devices; technology entrepreneurship; mechanical testing
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Research that will result in the eventual development of implantable medical devices must be of the highest scientific standard in order to help ensure patient safety. However, those of us who specialize in translational research also understand that other considerations must often be made when designing these projects. Future regulatory and reimbursement considerations must be made when setting up research on implantable medical devices. As a result, there is a higher probability that this research will be applied to, and be useful for, a commercially viable device.  

In order to showcase translational research, MDPI’s Bioengineering journal is offering a second Special Issue dedicated to research on implantable medical devices. The goal of this is to further highlight cutting-edge research that has a high probability of leading to either improvements or developments in medical implants. The research presented can range from basic science studies to biomechanics and biomaterials research used for testing in large animals. This Special Issue will include a broad range of novel research related to medical devices across all sectors.

Potential topics include, but are not limited to, research on the development and evaluation of implants in the following areas:

  • Orthopedic and spine;
  • Cardiovascular;
  • Pulmonary;
  • Neural;
  • Tissue-engineered products;
  • Drug delivery.

Prof. Dr. Elizabeth A Friis
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orthopedic and spine
  • cardiovascular
  • pulmonary
  • neural
  • tissue-engineered products
  • drug delivery

Published Papers (1 paper)

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Research

17 pages, 8083 KiB  
Article
The Effect of Mechanical Circulatory Support on Blood Flow in the Ascending Aorta: A Combined Experimental and Computational Study
by Sapir Hazan Shenberger and Idit Avrahami
Bioengineering 2024, 11(3), 238; https://doi.org/10.3390/bioengineering11030238 - 28 Feb 2024
Viewed by 799
Abstract
Percutaneous mechanical circulatory support (MCS) devices are designed for short-term treatment in cases of acute decompensated heart failure as a bridge to transplant or recovery. Some of the known complications of MCS treatments are related to their hemodynamics in the aorta. The current [...] Read more.
Percutaneous mechanical circulatory support (MCS) devices are designed for short-term treatment in cases of acute decompensated heart failure as a bridge to transplant or recovery. Some of the known complications of MCS treatments are related to their hemodynamics in the aorta. The current study investigates the effect of MCS on the aortic flow. The study uses combined experimental and numerical methods to delineate complex flow structures. Particle image velocimetry (PIV) is used to capture the vortical and turbulent flow characteristics in a glass model of the human aorta. Computational fluid dynamics (CFD) analyses are used to complete the 3D flow in the aorta. Three specific MCS configurations are examined: a suction pump with a counterclockwise (CCW) rotating impeller, a suction pump with a clockwise (CW) rotating impeller, and a discharge pump with a straight jet. These models were examined under varying flow rates (1–2.5 L/min). The results show that the pump configuration strongly influences the flow in the thoracic aorta. The rotating impeller of the suction pump induces a dominant swirling flow in the aorta. The swirling flow distributes the incoming jet and reduces the turbulent intensity near the aortic valve and in the aorta. In addition, at high flow rates, the local vortices formed near the pump are washed downstream toward the aortic arch. Specifically, an MCS device with a CCW rotating impeller induces a non-physiological CCW helical flow in the descending aorta (which is opposite to the natural helical flow), while CW swirl combines better with the natural helical flow. Full article
(This article belongs to the Special Issue Implantable Medical Devices: 2nd Edition)
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