Special Issue "The Role of Protein Complexes in Neurodevelopmental Disorders"
Deadline for manuscript submissions: closed (16 August 2023) | Viewed by 571
Interests: neuroscience; protein complex; psychiatric disorders
Interests: neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease; mitophagy
Neurodevelopmental disorders are multifaceted conditions involving the brain, which includes autism spectrum disorder, intellectual disability, attention deficit/hyperactivity disorder, and schizophrenia. Abnormal brain development results in deficits in cognition, communication, behavior, and motor skills. The mechanisms of neurodevelopmental disorders are complicated, and variants in many genes have been reported to be involved in these disorders. As an important modulation of protein functions, protein complexes, formed by protein–protein interactions, become more and more attractive in neurodevelopmental disorders. Many protein complexes have been reported by researchers that they play critical roles in brain development, and abnormal levels of these complexes lead to behavioral deficits in offspring in animal models; thus, they are implicated in neurodevelopmental disorders. Investigating the role of protein complexes in neurodevelopmental disorders can improve the mechanisms of these disorders and may improve the therapeutics of related diseases. In light of these premises, this Special Issue aims to present advanced studies about protein complexes involved in neurodevelopmental disorders. We welcome all submissions related to the topics mentioned above.
Dr. Ping Su
Dr. Tingxiang Yan
Dr. Shuxin Yan
Manuscript Submission Information
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- protein complex
- neurodevelopmental disorders
- autism spectrum disorder
- intellectual disability