Cyclodextrin-Based Materials and Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Materials Science and Engineering".
Deadline for manuscript submissions: closed (30 November 2020) | Viewed by 6913
Special Issue Editors
Interests: cyclodextrins; drug delivery systems; drug-in-cyclodextrins-in-colloidal systems; microparticulate systems
Special Issues, Collections and Topics in MDPI journals
Interests: cyclodextrins; drug delivery systems; drug-in-cyclodextrin-in-nanolipid carriers; oral administration; pediatric formulations; topical delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cyclodextrins (CDs) are cyclic oligosaccharides consisting of D-glucose units joined by α-1,4-glucosidic linkages. They present a truncated cone structure with a hydrophilic outer surface and a hydrophobic inner cavity able to partially or entirely accommodate suitably sized lipophilic molecules.
In the pharmaceutical field, CDs have primarily been applied to enhance drug efficacy. In fact, due to their solubilizing and stabilizing power towards drugs, they are able to improve drug bioavailability and/or reduce adverse effects after oral, parenteral or other routes of administration. However, there are many other applications of CDs, and not only in pharmaceutics but also in the food, cosmetics, textiles, biomedical, and analytical fields.
Recently, studies on nanosystems containing CDs have been receiving great attention in academic research due to the versatility of these systems and their significant opportunities in pharmaceuticals. It is well recognized that CDs are able to increase the entrapment capacity of nanoparticles. The peculiar structures of CDs enable the design and synthesis of CD-based polymers with the desired structures and functions, supramolecular assemblies, and hydrogels that are of particular interest in the field of biomedicine, allowing to improve the stabilization of drugs, their contact with biological membranes, and then their permeability and also to gain delivery of genes. Thus, CDs-based nanosponges have recently emerged in the field of nanotechnology and in particular for their pharmaceutical, biomedical, and biotechnological applications, due to their contribution to achieving foremost prerequisites such as solubility, stability, sustained release, enhancement of permeability and bioavailability, improved efficacy, and also their usefulness in enabling proteins and peptides delivery, stimuli-sensitive drug release, and ocular delivery.
We kindly invite you to submit full papers, communications and reviews regarding the above-described topics, dealing with CD-based materials and their applications.
Prof. Dr. Francesca Maestrelli
Dr. Marzia Cirri
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
