Feature Review Papers in Section Applied Biosciences and Bioengineering

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 6226

Special Issue Editors


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Co-Guest Editor
Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, 90127 Palermo, Italy
Interests: human anatomy, histology and embryology; oncology; advanced diagnostics; carcinogenesis; immunomorphology; extracellular vesicles; exosomes; heat shock proteins; molecular chaperons; chaperonins; chaperonopathies; chaperonotherapy

Special Issue Information

Dear Colleagues, 

This Special Issue “Feature Review Papers in Section Applied Biosciences and Bioengineering” will collect review papers in all the areas of interest covered by “Applied Biosciences and Bioengineering” (https://www.mdpi.com/journal/applsci/sections/Applied_Biosciences_Bioengineering).

We welcome multidisciplinary research in the following fields: advanced diagnostics, anatomy and histology, biochemistry, bioinformatics, biomaterials, biomechanics, biomedicine, biorobotics, biosensors, biosignal processing, biotechnology, cardiac bioengineering, clinical bioengineering, drug delivery, genetics, immunology and microbiology, life science, neural bioengineering, neuroscience, oncobiology, physiology, pulmonary bioengineering, tissue engineering, etc.

Prof. Dr. Francesco Cappello
Guest Editor

Dr. Stefano Burgio
Co-Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

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Research

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19 pages, 4986 KiB  
Article
On the Finite Element Modeling of the Lumbar Spine: A Schematic Review
by Vincenza Sciortino, Salvatore Pasta, Tommaso Ingrassia and Donatella Cerniglia
Appl. Sci. 2023, 13(2), 958; https://doi.org/10.3390/app13020958 - 10 Jan 2023
Cited by 4 | Viewed by 1816
Abstract
Finite element modelling of the lumbar spine is a challenging problem. Lower back pain is among the most common pathologies in the global populations, owing to which the patient may need to undergo surgery. The latter may differ in nature and complexity because [...] Read more.
Finite element modelling of the lumbar spine is a challenging problem. Lower back pain is among the most common pathologies in the global populations, owing to which the patient may need to undergo surgery. The latter may differ in nature and complexity because of spinal disease and patient contraindications (i.e., aging). Today, the understanding of spinal column biomechanics may lead to better comprehension of the disease progression as well as to the development of innovative therapeutic strategies. Better insight into the spine’s biomechanics would certainly guarantee an evolution of current device-based treatments. In this setting, the computational approach appears to be a remarkable tool for simulating physiological and pathological spinal conditions, as well as for various aspects of surgery. Patient-specific computational simulations are constantly evolving, and require a number of validation and verification challenges to be overcome before they can achieve true and accurate results. The aim of the present schematic review is to provide an overview of the evolution and recent advances involved in computational finite element modelling (FEM) of spinal biomechanics and of the fundamental knowledge necessary to develop the best modeling approach in terms of trustworthiness and reliability. Full article
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Review

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17 pages, 3787 KiB  
Review
Quantitative Assessment of Upper-Limb Volume: Implications for Lymphedema Rehabilitation?
by Lorenzo Lippi, Alessio Turco, Stefano Moalli, Mauro Nascimben, Claudio Curci, Alessandro de Sire, Lia Rimondini and Marco Invernizzi
Appl. Sci. 2023, 13(17), 9810; https://doi.org/10.3390/app13179810 - 30 Aug 2023
Cited by 4 | Viewed by 1204
Abstract
Upper-limb lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in the arm or hand, resulting in swelling and functional impairment. The accurate and reliable volumetric assessment of limb volume is crucial for the correct management of lymphedema. This narrative [...] Read more.
Upper-limb lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in the arm or hand, resulting in swelling and functional impairment. The accurate and reliable volumetric assessment of limb volume is crucial for the correct management of lymphedema. This narrative review provides an overview of the different methods proposed in the literature for the volumetric assessment of upper-limb lymphedema. In more detail, several methods of volumetric assessment have been proposed in recent years, including water displacement, the centimetric method, perometry, bioimpedance spectroscopy, dual-energy X-ray absorptiometry, magnetic resonance imaging, computed tomography, and three-dimensional laser scanning techniques. On the other hand, each method is characterized by specific strengths and limitations in terms of accuracy, reliability, practicality, and cost-effectiveness. Moreover, factors including operator experience, equipment availability, and patient population characteristics might have several implications in the optimal assessment of upper-limb volume. In this context, a precise volumetric assessment is crucial to improving the rehabilitation framework, patient education, and research outcomes. As a result, the integration of emerging technologies is needed to improve the tailored management of patients with upper-limb lymphedema. In conclusion, volumetric assessment methods provide valuable insights in the management of upper-limb lymphedema, improving patient care, treatment outcomes, and research advancements. Future research should focus on testing these innovative solutions on larger samples of patients to enhance the reproducibility, accuracy, accessibility, and clinical utility of volumetric assessment methods in the complex treatment framework of upper-limb lymphedema. Full article
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Other

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17 pages, 14340 KiB  
Systematic Review
A Systematic Review of Computational Fluid Dynamics Models in the Stomach and Small Intestine
by Nadun Palmada, Saeed Hosseini, Recep Avci, John E. Cater, Vinod Suresh and Leo K. Cheng
Appl. Sci. 2023, 13(10), 6092; https://doi.org/10.3390/app13106092 - 16 May 2023
Cited by 5 | Viewed by 2252
Abstract
The use of in silico models to improve our understanding of the fluid dynamics within the gastrointestinal tract has increased over the last few decades. Computational fluid dynamics (CFD) is an in silico technique that can be used to characterize and model the [...] Read more.
The use of in silico models to improve our understanding of the fluid dynamics within the gastrointestinal tract has increased over the last few decades. Computational fluid dynamics (CFD) is an in silico technique that can be used to characterize and model the fluid mechanics driving the digestion of food and absorption of nutrients. This systematic review outlines the current methodologies used to develop CFD models of the stomach and small intestine, and summarizes the flow and mixing patterns predicted from these models. A literature search was conducted on Scopus, and 15 stomach CFD studies and 15 small intestine CFD studies were included in this review after the literature selection and exclusion process. Two primary flow patterns; retropulsive flow and recirculation regions, were identified within the stomach CFD models. The flow patterns within the small intestine were depended on the type of motility pattern present. The shortcomings of the current models are discussed, and considerations for future gastric and intestinal flow modeling are provided. Full article
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