Nutraceuticals, Functional Foods and Health Effects

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: closed (20 August 2023) | Viewed by 1330

Special Issue Editors


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Guest Editor
Medicinal Plants & Economic Development (MPED) Research Centre, University of Fort Hare, Alice 5700, South Africa
Interests: functional foods; diabetes; obesity; cancer; malnutrition; gut microbiome; nanoparticles; medicinal plants

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Guest Editor
School of Health Sciences, University of Greenwich, Avery Hill Campus, London SE9 2UG, UK
Interests: nutrition; prebiotics; diabetes; glycaemic index of food; dietary fibre; gut microbiome
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Special Issue Information

Dear Colleagues,

The relationship between disease, lifestyle and diet has been established through various studies, leading to increasing demand for functional foods among consumers globally. Functional foods (natural, processed or conventional) contain known/unknown bioactive compounds, in defined, effective, and non-toxic amounts, that provide a clinically proven and documented health benefit for the prevention, management, or treatment of viral and chronic diseases. Nutraceuticals, on the other hand, are foods that provide the body with medical or health benefits, including nutrients for the prevention and treatment of a disease. 

Chronic non-communicable diseases (NCDs) and viral infections are the most common causes of premature death and morbidity around the world. These diseases also have a huge impact on health-care costs, productivity, and growth (Otunola and Martiryosan 2021). Examples are mental, eye and gut health, inflammation, ageing and beauty, cancer, gastrointestinal disorders, diabetes, obesity and cardiovascular diseases, among others.

Considerable interest has been expressed by manufacturers, consumers and health professionals in functional foods and nutraceuticals for obvious reasons, including the fact that the efficacy of synthetic drugs is limited by adverse side reactions (Singh et al., 2018). Although currently a small scientific field, functional foods and nutraceutical science is rapidly growing, as studies show that functional food products can help manage chronic disease and promote overall wellness. 

Therefore, this Special Issue is aimed at exploring the health benefits of functional foods and nutraceuticals for the prevention, care and management of chronic conditions. The focus would be on recipes, ingredients, methods, dosages, identification, development of functional foods, chemical characterization of active components, specific health benefits as well as the mechanisms of action. Myths and controversial results relevant to the topic would also be welcome. This will help validate and confirm the health potentials and bioactivity of functional foods and give scientific backing to the various claims for efficacy.

Dr. Gloria Aderonke Otunola
Prof. Dr. Omorogieva Ojo
Guest Editors

Manuscript Submission Information

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Keywords

  • functional foods
  • nutraceuticals
  • supplements
  • nutrients
  • viral infections
  • chronic diseases
  • mental health
  • gut microbiome
  • pro-/pre-biotics
  • bioactive
  • biomarkers
  • cancer
  • diabetes
  • obesity

Published Papers (1 paper)

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Research

11 pages, 2094 KiB  
Communication
Roles of Marine Shellfish Proteins with High Contents of Angiotensin-Converting Enzyme (ACE)-Binding Peptides in Nutrition Support for Hypertension
by Li Yang, Tianyu Shu, Kai Wang, Zhen Yuan and Xuewu Zhang
Appl. Sci. 2023, 13(8), 4654; https://doi.org/10.3390/app13084654 - 07 Apr 2023
Cited by 1 | Viewed by 932
Abstract
In this study, experimental tests, together with computer analyses, were carried out to identify the essential nutritional markers that can offer protein supplementation-based nutrition support for hypertension. In particular, 16 marine shellfish proteins were firstly screened for in silico hydrolysis by gastrointestinal enzymes [...] Read more.
In this study, experimental tests, together with computer analyses, were carried out to identify the essential nutritional markers that can offer protein supplementation-based nutrition support for hypertension. In particular, 16 marine shellfish proteins were firstly screened for in silico hydrolysis by gastrointestinal enzymes and then the binding abilities of the obtained oligopeptides to angiotensin-converting enzyme (ACE) were examined. In addition, the ACE inhibition activities of selected oligopeptides were assayed in vitro. It was discovered that mussel-derived NADH dehydrogenase and AMP-activated protein kinase and razor-clam-derived cytochrome b, NADH dehydrogenase, and ATP synthase were excellent sources of protein that are able to release a high amount of ACE-binding peptides. Meanwhile, four oligopeptides (SCCGY, SSGAW, PICQF, and IQPEW) were detected as strong ACE binders, with IC50 values of 0.09, 0.25, 0.41, and 0.60 mM, respectively. Therefore, our findings demonstrate that shellfish proteins can serve as nutritional support for hypertension when patients are supplemented with these markers. In particular, oligopeptides are identified as the most promising compounds. Full article
(This article belongs to the Special Issue Nutraceuticals, Functional Foods and Health Effects)
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