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Special Issue "The Role of Selenium/Selenoproteins in Metabolism and Diseases"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 31 December 2023 | Viewed by 5991
Special Issue Editors
Interests: selenium; selenoprotein; trace element; diabetes; fatty liver; glucose and lipid metabolism; metabolic disease; antioxidant
Interests: molecular nutrition; minerals; alternative protein; global food security; sustainable development; human health; metabolic disease; antioxidant; oxidative stress; signaling; functional genomics
Special Issues, Collections and Topics in MDPI journals
Special Issue in Antioxidants: Trace Elements Metabolism and Oxidative Stress
Special Issue Information
Selenium is an essential micronutrient to both higher animals and humans. After it was discovered as a metalloid in 1817, our knowledge of selenium has evolved with a number of milestone findings: acute and chronic toxicities, Se/vitamin E deficiency diseases, nutrient requirements, anticancer potential, the characterization and biosynthesis of selenoproteins, and functional genomics of the selenoproteome. Arguably, many, if not all, functions of selenium are mediated through selenoproteins that possess a wide range of pleiotropic properties, ranging from cellular redox control to body hormone biosynthesis and macronutrient metabolism. Therefore, selenium and selenoproteins play crucial roles in maintaining mammalian health and prevention against diseases. Consequently, derangements of the selenium metabolism and(or) selenoprotein function may be involved in the etiology of a broad spectrum of widespread diseases, such as obesity, metabolic syndrome, diabetes mellitus, nonalcoholic fatty liver disease, cardiovascular diseases, neurodegenerative diseases, cancer, thyroid disease, etc. It is intriguing that both the deficiency and excess of selenium/selenoproteins can result in a similar metabolic dysregulation and contribute to the onset and progression of the aforementioned diseases, indicating the importance of a fully balanced and coordinated role of selenium/selenoproteins in health. Despite notable advances in the field, much remains to be explored.
We recognize your excellent knowledge of the topic and contribution to the field, and would like to invite you to submit your latest research findings or a review article to this Special Issue. This Special Issue intends to assemble the current findings, status, and perspective concerning the role of selenium/selenoproteins in metabolism and diseases, covering, but not limited to, the following topics:
- Pathophysiology and molecular mechanisms of selenium/selenoproteins-related disorders;
- Selenium/selenoproteins on energy and macronutrient metabolism;
- Selenium/selenoproteins on energy and micronutrient and drug metabolism;
- Selenium/selenoproteins on neurodegenerations;
- Selenium/selenoproteins on oncology;
- Selenium/selenoproteins on immunity and infections (COVID-19, SARS, MERS, and pneumonia);
- Basic biology of selenium/selenoproteins (chemistry, biochemistry, molecular biology, and cell biology).
We look forward to your contribution.
Prof. Dr. Jun Zhou
Prof. Dr. Xingen Lei
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- functions of selenoproteins
- diet-related diseases
- metabolic derangement
- selenium in disease prevention
- selenium deficiency and overload