Special Issue "Molecular Targets of Oxidative Stress: Focus on the Nrf2 Signaling Pathway in Health and Disease"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (20 August 2023) | Viewed by 25848
2. Inserm U1179 and ISPC-preclinical laboratory, University of Paris Saclay (UVSQ), 78000 Versailles, France
Interests: immune regulation; immunology of infectious diseases; innate immunity; oxidative stress; Nrf2; respiratory diseases; macrophage; exercise
Special Issues, Collections and Topics in MDPI journals
Oxidative stress, known to increase the risk of multiple metabolic and chronic disorders or cancer development, is defined by an imbalance between the production of reactive oxygen species (ROS) and the capacity of antioxidants to counteract the deleterious effects of oxidants. To regulate the oxidation/reduction (redox) balance, numerous antioxidant enzymes and nonenzymatic antioxidants exist. Free radicals activate transcription factors to promote antioxidants production and mitochondrial biogenesis. One of these transcription factors, nuclear factor erythroid 2-related factor 2 (Nrf2), is a master regulator of the antioxidant and anti-inflammatory responses. Indeed, Nrf2 contributes to redox balance by initiating the transcription of hundreds of genes involved in the antioxidant and cytoprotective responses. A better understanding of the molecular targets of oxidative stress and their interaction with the Nrf2 signaling pathway would strengthen the relevance of their preventive or therapeutic use in health and diseases.
We invite researchers to submit original articles or review articles on different aspects of the modulation of oxidative stress in animal models or in humans. The topic includes the biological and physiological effects of the Nrf2 signaling pathway in chronic diseases or their prevention.
Prof. Dr. Marcel Bonay
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
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