The Role of Oxidative Stress in Liver Cancer
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (20 February 2024) | Viewed by 1537
Special Issue Editors
Interests: medicine; biochemistry; cellular and molecular biology
Special Issue Information
Dear Colleagues,
Oxidative stress (OS) is known to be associated with the development of hepatocellular carcinoma (HCC), which can arise from NAFLD (nonalcoholic fatty liver disease); recent evidence has shown that a significant proportion of NASH (nonalcoholic steatohepatitis) patients develop HCC in the absence of cirrhosis. However, the mechanisms between OS and HCC are still unclear, making their clarification of extreme interest. In this scenario, the elucidation of the impact of OS on the development of liver carcinogenesis as well as on the prevention and treatment of liver cancer will be the focus of this Special Issue.
We invite you to submit your latest research findings or review articles to this Special Issue, including both in vitro and in vivo studies relating to the following topics:
- OS and related molecules as promoters of HCC;
- OS as a modulator of chronic inflammation and fibrosis arising during HCC development;
- the peculiar role for OS in non-alcoholic fatty liver disease (NAFLD), its evolution to the inflammatory complication non-alcoholic steatohepatitis (NASH) and the final transition from NASH to HCC;
- OS as a target of therapy to reduce development and progression of HCC.
We look forward to your contribution.
Dr. Erica Novo
Dr. Claudia Bocca
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- HCC
- NAFLD
- NASH
- inflammation
- liver fibrosis
- cirrhosis
