Natural Antioxidants and the Immunomodulation of Chronic and Transmissible Diseases
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (10 September 2023) | Viewed by 4728
Special Issue Editors
2. University Hospital of Santa Maria- Brazilian Hospital Services Company (HUSM-EBSERH), 1000 Roraima Avenue, Santa Maria, Brazil
Interests: nutritional genomics; immunosenescence; superoxide-hydrogen peroxide imbalance; aging and age-related degenerative disorders; amazonian diet
Interests: pharmacogenomics; cancer; oxidative stress and antioxidants; biogerontology; herbal medicines in wound healing
Special Issue Information
Dear Colleagues,
Oxidative metabolism is a critical component in maintaining homeostasis and biological function. With aging, this metabolism, which continuously produces pro-oxidative molecules and endogenous antioxidants, tends to change mainly due to the decline in the mitochondrial and autophagic function of cells. Oxidative stress triggers a cascade of events that leads to immunosenescence characterized by the establishment of patterns of chronic inflammatory states associated with the risk and progression of non-transmissible diseases. In addition, it can negatively impact the immune efficiency against pathogens, increasing the risk of hospitalization and infection-related deaths. The evidence suggests that natural antioxidants in foods and phytotherapeutics have immunomodulatory action, attenuating low-grade inflammatory states and improving the immune response. However, most of this evidence has been published in a scattered manner, which makes it challenging to build systematic knowledge about the impact of natural antioxidants on immunomodulation.
Therefore, this Special Issue aims to provide a broad and updated overview of the antioxidant's impact on immunosenescence, non-transmissible diseases associated with chronic inflammation, and efficiency improvement of the immune response to pathogens, especially viruses and bacteria. Contributions by experts in the field in the form of research papers and critical reviews involving the description of biological mechanisms and the therapeutic potential of natural antioxidants are welcome.
Dr. Ivana Beatrice Mânica Da Cruz
Dr. Fernanda Barbisan
Guest Editors
Manuscript Submission Information
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Keywords
- antioxidants as novel therapeutic approaches
- cancer
- cardiovascular diseases
- diabetes
- immunosenescence
- immunomodulation
- infections conditions
- inflammation
- musculoskeletal conditions
- neurodegenerative diseases
- psychiatric disorders
- skin healing and aging