Special Issue "The Role of Oxidative Stress in Vascular Disease Associated with Diabetes"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 10 March 2024 | Viewed by 8111
2. Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, University of Coimbra, Azinhaga de Santa Comba, Celas, 3000-548 Coimbra, Portugal
Interests: obesity; diabetes; vascular dysfunction; oxidative stress; therapeutics; prevention
Obesity and diabetes are major health problems with a great impact on public health and increasingly gaining prevalence worldwide. Unhealthy diets and physical inactivity lead to obesity and subsequently induce insulin resistance which is a major risk factor for diabetes and cardiovascular diseases. Oxidative stress and inflammation are underlying mechanisms of endothelial dysfunction leading to vascular dysfunction, either of small or large blood vessels, in diabetic patients. There are several biomarkers of oxidative stress and inflammation available for assessing the therapeutic response to interventions, but few are currently recommended for clinical use. Moreover, the trend toward personalized medicine and individualized risk assessment during recent years is growing strong and various functional and imaging screening tests, including endothelial function studies, have been suggested to improve accuracy and provide the functional implications of the risk factors to monitor vascular disease.
This Special Issue will focus on the role of oxidative stress on vascular disease associated with diabetes emphasizing the need for biomarkers clinically relevant and new therapeutical interventions. The future of preventive and personalized medicine will reduce the burden of cardiovascular complications associated with diabetes.
Dr. Cristina M. Sena
Manuscript Submission Information
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- vascular dysfunction
- oxidative stress