Catalytic Antioxidants Volume 2

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".

Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 182

Special Issue Editor

Department of Chemistry “Ugo Schiff”, University of Florence, Via Della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy
Interests: design, synthesis and structure-activity relationship of bio-inspired multi-defence antioxidants; chalcogen containing phenolic antioxidants; macromolecular and nano-supported antioxidants
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The formation of free radicals and other reactive oxygen species (ROS) in living tissues is an unavoidable consequence of aerobic metabolism. Today, it is well recognized that oxygen-centered free radicals are also useful intermediates involved in crucial biochemical transformations. However, it has been solidly demonstrated that an anomalous high concentration of ROS is directly related to tissue oxidative stress, thus origin and consequence of many diseases and ageing itself. Evolution provided endogenous and exogenous defenses for keeping the ROS concentration under control. The intake of small molecules capable of inhibiting chain radical oxidations and oxidative damage is a simple and efficient exogenous solution. A diet rich in antioxidants can play a crucial role in health, particularly in countries where the factors responsible for dangerously increasing the concentration of ROS (stress, smoke, over alimentation, alcohol and drug abuse, and pollution) are frequent lifestyle components. On the other hand, the expression of specific enzymes capable of avoiding the formation of ROS or to quench dangerous free radicals (i.e., superoxide dismutase, catalase, glutathione peroxidase) are an endogenous answer to this problem. In the last year, a remarkable effort has been made to study antioxidants that can mimic these enzymes, ensuring protection despite being used in catalytic amounts. This enzyme mimicry can be achieved either by favoring a disproportionation process (for example, in superoxide dismutase or catalase-like systems) or by exploiting a sacrificial reductant consumed during the process (for example, in glutathione peroxidase mimic compounds).

Volume 1 of a Special Issue on ‘Catalytic Antioxidants’ published four original papers and two reviews, we are ready to start with Volume 2.

The aim of this Volume 2 Special Issue of Antioxidants is to present a collection of the latest research on catalytic antioxidants. We welcome papers focused on molecular actions at the biological level of natural derivatives, as well as papers related to the design, synthesis, and effectiveness of synthetic catalytic antioxidants derivatives.

Prof. Dr. Stefano Menichetti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • catalytic antioxidants
  • enzyme-like activity
  • bioinspired design

Published Papers

There is no accepted submissions to this special issue at this moment.
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