Special Issue "Redox Regulation in Inflammation and Disease – 2nd Edition"
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 4564
Interests: (extracellular) redox regulation; signal transduction; Trx family proteins; cell communication; (neuro-) inflammation; translational immunology
Special Issues, Collections and Topics in MDPI journals
We are delighted to be organizing Volume 2 of this Special Issue, entitled “Redox Regulation in Inflammation and Disease”, especially given the success of Volume 1, which you can read here, along with other publications, free of charge:
We distinguish oxidative eu- and distress, acknowledging the role of various factors such as i) the regulated enzymatic production and decay of specific reactive oxygen species (ROS), ii) their role as second messengers, iii) the presence of regulatory thiol switches and their function in redox-mediated signaling.
Specific ROS such as hydrogen peroxide, hydrogen sulfide, and nitric oxide are essential for physiological processes including inflammatory signaling. Redox regulation of membrane proteins, enzymes, and transcription factors such as NFκB is crucial for the activation and migration of immune cells, the production and release of immune mediators, and cell communication. Interestingly, extracellular redox proteins, low-molecular-weight thiols, and thiol switches also affect signal transduction and cell communication. Redox changes can be analyzed in body fluids and isolated immune cell populations without using invasive and expensive techniques, maintaining their potential for developing new preventive and diagnostic tools and innovative treatments.
For this Special Issue, we invite researchers to provide original research articles that report results combining the fields of redox regulation, inflammatory signaling, and translational immunology, highlighting which specific reactive species and/or thiol switches are involved. We also invite the submission of clinical studies demonstrating relevant changes in the levels or activities of i) redox proteins, ii) low-molecular-weight thiols, and/or iii) altered redox states of particular proteins in diseases linked to inflammation. Review articles discussing the current state of the art are also welcome.
Dr. Eva-Maria Hanschmann
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- redox signaling
- reactive oxygen and nitrogen species
- signal transduction
- thiol switches
- regulation of immune cells
- translational immunology