Food Antioxidants and Gut Microbial Communities

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Natural and Synthetic Antioxidants".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 1462

Special Issue Editors

Department of Animal Sciences, McGill University, Sainte-Anne-de-Bellevue, Quebec, QC H9X 3V9, Canada
Interests: probiotics; prebiotics; antimicrobial resistance; microbiome; new antibiotics
Special Issues, Collections and Topics in MDPI journals
State Key Laboratory of Animal Nutrition and Feeding, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China
Interests: plant extracts; gut microbiota; nutritional regulation; livestock quality; antibiotic alternatives
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dietary changes may lead to significant changes in the structure and function of host gut microbial communities. Food antioxidants including antioxidant vitamins, dietary polyphenols, flavonoids, carotenoids, and bioactive peptides are necessary nutrients required by the body to balance the oxidative stress generated by various biochemical and metabolic reactions. Several in vitro, animal model, and clinical studies indicate that food antioxidants might enhance gut microbial communities, which possess many health benefits in multiple oxidative stress-related diseases, such as cardiovascular disease, cancer, diabetes, obesity, etc. Antioxidant compounds from several food sources improve host health by regulating the structure as well as the function of gut microbiota. On the other hand, the homeostasis between gut microbial communities and the generation of reactive oxygen species might be altered by food antioxidants. Increasing attention has been paid to food antioxidants that might aid in developing gut microbe-targeting therapeutics for various diseases, leading to calls for more mechanistic investigations. Still, further clarification in certain microbial species caused by food additives is needed. Additionally, whether gut microbiota influenced by food antioxidants could modulate immune function and metabolites that translocate into circulation needs further investigation.

This Research Topic is open to reviews and original articles dealing with, but not limited to:

  • The in vivo effects of food antioxidants: types, modes of action, and impacts on gut microbial communities;
  • The interplay of dietary antioxidants and gut microbiome in human and animal health;
  • Clinical trials of food antioxidants’ impacts on human health and the gut microbiome;
  • The impact of food antioxidants on gut microbe-targeting therapeutics for various diseases.

Prof. Dr. Xin Zhao
Dr. Wei Si
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antioxidants
  • gut microbiome
  • food additive

Published Papers (1 paper)

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Review

34 pages, 2018 KiB  
Review
Tumor Microbial Communities and Thyroid Cancer Development—The Protective Role of Antioxidant Nutrients: Application Strategies and Future Directions
by Francesca Gorini and Alessandro Tonacci
Antioxidants 2023, 12(10), 1898; https://doi.org/10.3390/antiox12101898 - 23 Oct 2023
Cited by 1 | Viewed by 1158
Abstract
Thyroid cancer (TC), the most frequent malignancy of the endocrine system, has recorded an increasing incidence in the last decades. The etiology of TC remains at least partly unknown and, among modifiable risk factors, the gut microbiota and dietary nutrients (vitamins, essential microelements, [...] Read more.
Thyroid cancer (TC), the most frequent malignancy of the endocrine system, has recorded an increasing incidence in the last decades. The etiology of TC remains at least partly unknown and, among modifiable risk factors, the gut microbiota and dietary nutrients (vitamins, essential microelements, polyphenols, probiotics) have been recognized to not only influence thyroid function, but exert critical effects on TC development and progression. Recent discoveries on the existence of tumor microbiota also in the TC microenvironment provide further evidence for the essential role of tumor microorganisms in TC etiology and severity, as well as acting as prognostic markers and as a potential target of adjuvant care in the treatment of TC patients. Therefore, in this review, we summarize current knowledge on the relationship of the tumor microbiome with the clinical tumor characteristics and TC progression, also illustrating the molecular mechanisms underlying this association, and how antioxidant nutrients may be used as a novel strategy to both control gut health and reduce the risk for TC. Furthermore, we discuss how new technologies might be exploited for the development of new foods with high nutritional values, antioxidant capability, and even attractiveness to the individual in terms of sensory and emotional features. Full article
(This article belongs to the Special Issue Food Antioxidants and Gut Microbial Communities)
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