Dear Colleagues, 

Our previous Special Issue on the “Antioxidant Activity of “Polyphenolic Food” and Human Health—2nd Edition” (https://www.mdpi.com/journal/antioxidants/special_issues/Polyphenolic_Food_Health_2nd), published in the 2022 volume of Antioxidants, received a vast number of submissions and was a successful compilation of research and review articles. As this is a rapidly evolving topic, we would like to further explore the role of polyphenolic food in human health with another Special Issue for the year 2023.

Traditionally, many medicinal products have been derived from natural compounds with healing properties. Functional and nutraceutical foods provide an alternative to aid in the management of various diseases. With the development of research on nutraceuticals, it is becoming apparent that many of the positive capabilities of these compounds are at least partly due to the presence of polyphenols.

Dietary polyphenols are abundant in plant-based foods such as fruits, vegetables, dry legumes, cereals, olives, cocoa, tea, coffee and wine, the so-called “polyphenolic food”.

Research into the beneficial health effects of polyphenols has increased considerably over the last two decades. Polyphenols have shown antimicrobial, antioxidant, anti-inflammatory, anticarcinogenic, antidiabetic,  antiadipogenic and neuroprotective effects. Polyphenols may also counteract apoptosis and cytotoxicity due to their immunomodulatory properties and regulate innate and adaptive immunity. Polyphenols have also been shown to reduce oxidative stress and inflammation, modulate immune cells, and regulate gut microbiota composition. Polyphenols could beneficially impact a number of chronic diseases. The consumption of food that is rich in phenolic compounds, “polyphenolic food”, represents a promising therapeutic method to prevent many chronic diseases and improve health.

We believe that this Special Issue, “Antioxidant Activity of Polyphenolic-Food and Human Health” (third edition), will help to highlight the most recent advances in all aspects of polyphenols, including their extracts, and health-enhancing benefits.

This Special Issue of Antioxidants welcomes the submission of research articles, review articles, systematic reviews, meta-analyses and short communications.

Prof. Dr. Stefania D'Angelo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• antioxidants
• anti-inflammatory
• anti-obesity
• functional food
• human health
• Mediterranean diet
• nutraceuticals
• nutrition
• oxidative stress
• polyphenols