Advances in Bispecific Antibodies
A special issue of Antibodies (ISSN 2073-4468).
Deadline for manuscript submissions: closed (30 September 2016) | Viewed by 56354
Interests: immunotherapy of cancer; bispecific antibodies; T cell bispecific antibodies
Special Issues, Collections and Topics in MDPI journals
Bispecific antibodies have been the focus of antibody engineers almost since the discovery of therapeutic antibodies. These antibodies offer plenty of possibilities for improving the properties of conventional antibodies. Based on the modular design of immunoglobulins, a huge “zoo” of different bispecific antibody formats has been developed in recent decades. However, for many years, the development of these bispecific antibodies for clinical trials has been slow, due to various issues, such as technical challenges with production and short half-lifes. Only now have a significant number of bispecific antibodies (based on different designs) reached the clinic. This Special Issue of "Antibodies" focuses on our progress with bispecific antibodies, with respect to engineering, therapeutic applications, and those bispecific antibodies in preclinical and clinical development.
Dr. Christian Klein
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- bispecific antibody
- antibody engineering
- T cell recruitment