Autoantibodies in Systemic Sclerosis

A special issue of Antibodies (ISSN 2073-4468).

Deadline for manuscript submissions: closed (31 May 2019) | Viewed by 619

Special Issue Editors

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Guest Editor
Department of Rheumatology and clinical Immunology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece
Interests: HLA-DR genes in autoimmune diseases; cytokines psoriatic arthritis; T cells and B cells in systemic sclerosis; dietary supplements in inflammatory diseases

E-Mail Website
Guest Editor
Department of Rheumatology and Clinical Immunology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece
Interests: autoimmunity; autoimmune diseases; diet; immunosupression; immunoregulation; microbiome; nutrition; rheumatic diseases
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Special Issue Information

Dear Colleagues,

Systemic sclerosis (SSc) is a complex disease characterized by microvasculopathy, extensive fibrosis and disease-related autoantibodies.  The disease frequently causes organ damage with poor outcome. Therefore early recognition of the disease and /or prediction of its course is of paramount importance in order to improve optimal management and patient survival.  Autoantibodies, a hallmark of B cell autoimmunity, are of particular interest in SSc, a disease with no overt inflammatory infiltrates. Many autoantibodies are detected in SSc, few are included in the classification criteria for the disease, some are associated with clinical manifestations, and some are of pathogenic significance. Autoantibodies in SSc may also indicate the co-existence of other autoimmune rheumatic diseases. Why SSc is characterized by a diverse spectrum of autoantibody responses remains unclear, though pathogens and exogenous triggers have been considered likely triggers. Thus, the pathogenic, diagnostic and clinical significance of autoantibodies in SSc is a focus of intense research.

This Special Issue of Antibodies focuses on autoantibodies in SSc and authors are invited to submit original papers or reviews on the following topics of autoantibodies in SSc: origin, pathogenic role, diagnostic significance, clinical associations, prognosis, and cancer associations.

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Systemic sclerosis
  • autoantibodies
  • autoimmunity
  • association
  • biomarker
  • classification

Published Papers

There is no accepted submissions to this special issue at this moment.
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