The Ecological Role of Antibiotic Production in Bacteria

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "The Global Need for Effective Antibiotics".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 4023

Special Issue Editor

University Hospital Frankfurt, Department of Internal Medicine I, Goethe University Frankfurt, 60590 Frankfurt, Germany
Interests: bacteriology; microbiome; metabolomics; antibiotics; microbial ecology; NAFLD; liver cirrhosis; ACLF

Special Issue Information

Dear esteemed colleagues,

Antibiotic research has made huge progress, especially in the middle decades of the 20th century, resulting in the discovery of many novel antibiotics. To date, most of the compounds with antimicrobial activity were obtained from soil- bacteria. In bacterial communities, inter-specific competition for nutrients is a major type of interaction. An important survival strategy in this competition is interference competition, which is the production of secondary metabolites with antimicrobial activity that can suppress or kill microbial opponents. In nature, antibiotics may be produced after receiving specific environmental signals or signals from surrounding microorganisms. So far, there is no scientific consensus on the ecological role of antibiotics and why they are produced. With this Special Issue, we would like to give an overview of the current status of antibiotic discovery from bacteria and the ecological role of antibiotic production in bacteria.

We invite authors to submit original research and review articles regarding the discovery of novel antimicrobial compounds from bacteria and their ecological role in bacteria including, but not limited to the following topics:

  • Antibiotic production in bacteria
  • Antimicrobial activity
  • Ecological role of antibiotics
  • Microbial ecology
  • Inter-specific bacterial interactions
  • Screening for novel secondary metabolites with antimicrobial activity
  • Novel natural products from bacteria

This Special Issue of the Antibiotics Journal aims to reflect the current status of antibiotic discovery from bacteria and the ecological role of antibiotic production in bacteria. Here we aim to bring together biologists, microbiologists, ecologists, chemists, and bioinformaticians to highlight the progress in the field of antibiotic research in microbial ecology.


Dr. Olaf Tyc
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobials
  • antimicrobial activity
  • soil-bacteria
  • secondary metabolites
  • volatiles
  • microbial interactions
  • microbial ecology
  • natural products
  • competition
  • microbial ecology

Published Papers (1 paper)

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Review

15 pages, 1624 KiB  
Review
Air Ambulance: Antimicrobial Power of Bacterial Volatiles
by Alexander Lammers, Michael Lalk and Paolina Garbeva
Antibiotics 2022, 11(1), 109; https://doi.org/10.3390/antibiotics11010109 - 14 Jan 2022
Cited by 13 | Viewed by 3096
Abstract
We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be [...] Read more.
We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis. Full article
(This article belongs to the Special Issue The Ecological Role of Antibiotic Production in Bacteria)
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