Antimicrobial Resistance and Antimicrobial Activity of Natural Products and Derivatives

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 230

Special Issue Editors

Department of Medical Microbiology & Immunology (MMI), RAK College of Medical Sciences (RAKCOMS), RAK Medical & Health Sciences University (RAKMHSU), Ras Al Khaimah, United Arab Emirates
Interests: antimicrobial resistance; diagnostic microbiology; immunology and antimicrobial agents
Special Issues, Collections and Topics in MDPI journals
Department of Medical Microbiology & Infectious Diseases, Erasmus University Medical Center Rotterdam (Erasmus MC), 3015 GD Rotterdam, The Netherlands
Interests: medical microbiology; antimicrobial resistance; susceptibility testing and serology

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) refers to the capability of microorganisms to resist the effects of antimicrobials that were previously effective in treating infections caused by them. This resistance can occur naturally or be selected through genetic mutations or acquired by the transfer of resistance genes between microorganisms. The overuse and misuse of antibiotics and other antimicrobial drugs are the leading causes of AMR. When antibiotics are prescribed unnecessarily, or when patients do not complete their full course of antibiotics, the bacteria that caused the infection can develop resistance to the drug, making it ineffective in treating the same infection. AMR is a growing public health threat that can contribute to increased morbidity, mortality, and healthcare costs. It can also limit the effectiveness of medical procedures such as chemotherapy, surgery, and organ transplantation. Preventing and controlling AMR requires a coordinated effort from healthcare providers, patients, and policymakers, including the responsible use of antibiotics and the development of new antimicrobial drugs.

The use of natural products as antimicrobial agents has attracted renewed interest in recent years, especially with the emergence of drug-resistant bacteria. Natural products have the potential to act as antimicrobial agents through various mechanisms, including inhibition of cell wall synthesis, disruption of membrane integrity, inhibition of protein synthesis, inhibition of DNA synthesis, and interference with metabolic pathways. Some examples of natural products with antimicrobial activity include: Plant-derived compounds (such as alkaloids, flavonoids, terpenoids, and phenolics), Essential oils, Marine-derived compounds and Microbial-derived compounds.  Despite the antimicrobial potential of natural products, there are several challenges that need to be overcome. These include the difficulty in obtaining sufficient quantities of some natural products, the complexity of their chemical structures, and the lack of standardized methods for evaluating their efficacy and safety. In conclusion, natural products have the potential to act as effective antimicrobial agents, and further research is needed to explore their potential for use in clinical settings.

This Special Issue therefore encourages authors to provide the public with cutting-edge original scientific manuscripts and reviews on the following topics:

  1. Antimicrobial Resistance
  2. Antimicrobial Activity of Natural Products and Derivatives

Dr. Godfred A. Menezes
Dr. Wil Goessens
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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