Special Issue "Fungal Secondary Metabolites"
Deadline for manuscript submissions: closed (29 February 2020) | Viewed by 21436
Interests: applied microbiology; isolation and taxonomy of Actinomycetes; natural substances from microorganisms; development of isolation methods for unknown microorganisms
Interests: endophytic fungi; secondary products
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Special Issue in Antibiotics: Top 10 of Antibiotics Travel Awards 2019
Special Issue in Antibiotics: Novel Fungal Metabolites with Antimicrobial Activities
Eubacteria and fungi have been mainly used for searching for biologically active substances derived from microorganisms. Among eubacteria, actinomycetes, a producer of streptomycin and avermectin, has been used as a search source for antibiotics. In these processes, gentamicin, amphotericin B, tacrolimus, etc., were discovered and contributed greatly to humanity as pharmaceuticals. “Actinomycetes” was planned as a Special Issue of Antibiotics in 2018, and many interesting reviews were published.
On the other hand, penicillin, discovered as a metabolite of fungi in 1929 by Alexander Fleming, has contributed greatly to human survival as an anti-infective agent, and its improved analogs are still the most frequently used antibiotics. The reason for this is that its mechanism of action is the inhibition of bacterial cell wall synthesis and shows excellent selective toxicity. The statin compounds also produced by fungi are widely used as a prophylactic and therapeutic agent for antihyperlipidemia or arteriosclerosis. Micafungin, having effective activity against Asperugilus or Candida infection, were also found from secondary metabolites of fungi.
According to the Dictionary of Natural Products (2018 edition), the compounds produced by eubacteria or fungi are almost half each. Therefore, in this Special Issue we will focus on fungi, especially microscopic fungi, and we would like to address the diversity and efficacy of the produced compounds, the relation between characteristic forms and substance production, and recent topics.
Prof. Dr. Yoko Takahashi
Prof. Dr. Gary A. Strobel
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- filamentous fungi
- secondary metabolites
- bioactive substances
- diversity of structure
- mode of action
- genetic engineering
- genome mining
- extreme habitats