Dear Colleagues,

In recent decades, antimicrobial resistance has emerged as one of the most significant public health challenges and will continue to pose a threat to public health in the future. Since last-line antimicrobial treatments increasingly fail, there is an urgent need to discover and develop new antibacterial agents and drug-resistant inhibitors, as well as controlling the "uncontrolled" or abusive use of both old antimicrobials or new antimicrobials. Over the last decade, many research groups have focused their work on the discovery, optimization and validation of new antimicrobials. This extensive search for new antimicrobials is being carried out on both land and at sea, yielding new marine drugs and new compounds obtained from plants or animals, with an ultimate focus on microscopic bacteria and viruses as sources of new antimicrobials. To make present and future research advances in these fields more concise, it is necessary to condense the vast number of available studies into reviews and mini-reviews to save researchers hours of time conducting bibliometric searches, allowing them to steer their research in the right direction. Reviews on new antimicrobial agents can cover any of the following topics:

• Modifications of antimicrobial agents;
• New uses of antimicrobial agents;
• Legislation regarding the control of antimicrobial agents;
• Antimicrobial resistance to antimicrobial agents;
• Genomics with regard to antimicrobial agents resistance;
• Transcriptomics with regard to antimicrobial agents;
• Proteomics and metabolomics with regard to antimicrobial agents;
• Additive combination of antimicrobial agents;
• Combination of antimicrobials with other therapeutic opportunities;
• Traceability of the use of antimicrobial agents;
• Traceability of antimicrobial resistance;
• Clinical uses of antimicrobial agents;
• Non-clinical uses of antimicrobial agents;
• Drug-resistant inhibitors.

This Special Issue of Antibiotics in the section “Novel Antimicrobial Agents” covers a selection of the best reviews and/or mini-reviews on the most recent and innovative developments of antimicrobial agents. We hope that this Special Issue can further encourage and promote the scientific contributions of researchers in this important field.

Prof. Dr. Carlos M. Franco
Guest Editor

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