Special Issue "Featured Reviews in Novel Antimicrobial Agents"

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 1456

Special Issue Editor

Department of Analytical Chemistry, Nutrition and Bromatology, Faculty of Veterinary Science, University of Santiago de Compostela, 27002 Lugo, Spain
Interests: food safety; analytical chemistry; food microbiology; antimicrobial resistant bacteria; food-borne pathogens; transcriptomics; genotyping; chromatography; mass spectrometry; biofilms; antimicrobial detection; microbiome
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Special Issue Information

Dear Colleagues,

In recent decades, antimicrobial resistance has emerged as one of the most significant public health challenges and will continue to pose a threat to public health in the future. Since last-line antimicrobial treatments increasingly fail, there is an urgent need to discover and develop new antibacterial agents and drug-resistant inhibitors, as well as controlling the "uncontrolled" or abusive use of both old antimicrobials or new antimicrobials. Over the last decade, many research groups have focused their work on the discovery, optimization and validation of new antimicrobials. This extensive search for new antimicrobials is being carried out on both land and at sea, yielding new marine drugs and new compounds obtained from plants or animals, with an ultimate focus on microscopic bacteria and viruses as sources of new antimicrobials. To make present and future research advances in these fields more concise, it is necessary to condense the vast number of available studies into reviews and mini-reviews to save researchers hours of time conducting bibliometric searches, allowing them to steer their research in the right direction. Reviews on new antimicrobial agents can cover any of the following topics:

  • Modifications of antimicrobial agents;
  • New uses of antimicrobial agents;
  • Legislation regarding the control of antimicrobial agents;
  • Antimicrobial resistance to antimicrobial agents;
  • Genomics with regard to antimicrobial agents resistance;
  • Transcriptomics with regard to antimicrobial agents;
  • Proteomics and metabolomics with regard to antimicrobial agents;
  • Additive combination of antimicrobial agents;
  • Combination of antimicrobials with other therapeutic opportunities;
  • Traceability of the use of antimicrobial agents;
  • Traceability of antimicrobial resistance;
  • Clinical uses of antimicrobial agents;
  • Non-clinical uses of antimicrobial agents;
  • Drug-resistant inhibitors.

This Special Issue of Antibiotics in the section “Novel Antimicrobial Agents” covers a selection of the best reviews and/or mini-reviews on the most recent and innovative developments of antimicrobial agents. We hope that this Special Issue can further encourage and promote the scientific contributions of researchers in this important field.

Prof. Dr. Carlos M. Franco
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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The Discovery of Novel Antimicrobial Agents through the Application of Isocyanide-Based Multicomponent Reactions
Antibiotics 2023, 12(5), 849; https://doi.org/10.3390/antibiotics12050849 - 04 May 2023
Viewed by 1195
Multicomponent reactions (MCR) have been used to synthesize a wide range of analogs from several classes of heterocyclic compounds, with multifaceted medicinal uses. The synthesis of highly functionalized molecules in a single pot is a unique property of MCR, allowing researchers to quickly [...] Read more.
Multicomponent reactions (MCR) have been used to synthesize a wide range of analogs from several classes of heterocyclic compounds, with multifaceted medicinal uses. The synthesis of highly functionalized molecules in a single pot is a unique property of MCR, allowing researchers to quickly assemble libraries of compounds of biological interest and uncover novel leads as possible therapeutic agents. Isocyanide-based multicomponent reactions have proven to be extremely effective at swiftly specifying members of compound libraries, particularly in the discovery of drugs. The understanding of structure–activity correlations that drive the development of new goods and technology requires structural variety in these libraries. In today’s world, antibiotic resistance is a major ongoing problem that poses risks to public health. The implementation of isocyanide-based multicomponent reactions upholds a significant potential in this regard. By utilizing such reactions, new antimicrobial compounds can be discovered and subsequently used to fight against such concerns. This study discusses the recent developments in antimicrobial medication discovery using isocyanide-based multicomponent reactions (IMCRs). Furthermore, the article emphasizes the potential of IMCRs (Isocyanide-based multicomponent based reactions) in the near future. Full article
(This article belongs to the Special Issue Featured Reviews in Novel Antimicrobial Agents)
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