Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.5
4.8
Journals
Antibiotics
Special Issues
Antibiotics and Environment − Research and Development toward the One...
share announcement

Antibiotics and Environment − Research and Development toward the One Health Approach

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 30 June 2024 | Viewed by 7637

Special Issue Editor

Dr. Takashi Azuma

E-Mail Website
Guest Editor
Department of Pharmacy, Osaka Medical and Pharmaceutical University, 4-20-1 Nasahara, Takatsuki 569-1094, Osaka, Japan
Interests: antibiotics; occurrence; wastewater; river; aquatic environment; ecotoxicity; antimicrobial-resistance (AMR); advanced water treatment; environmental risk assessment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Research on health and environmental risk assessments and countermeasures against antimicrobial resistance (AMR) are ongoing across the globe. The spread of antimicrobial-resistant bacteria is causing increasing concern about the future of antimicrobial use and other measures to control infectious diseases, and the problem of antimicrobial-resistant bacteria is now considered an important issue that requires urgent countermeasures and effective action by the World Health Organization (WHO). In addition to clinical cases, community-acquired infections caused by healthy carriers and outbreaks of antimicrobial-resistant strains originating from livestock, fisheries, and other industries are also becoming problematic. It is essential to comprehensively understand the trend of antimicrobial-resistant bacteria on a global scale, and a one health approach is desired to combat all of these problems.

The problem of antimicrobial-resistant bacteria in the environment manifests itself in a wide variety of systems originating from humans and animals, which occur simultaneously in a complex mixture of these systems. Assessing the present situation, clarifying the occurrence and fate in the environment, assessing environmental risks, and taking effective measures to reduce or mitigate risks are methods that can provide useful knowledge for finding a point of coexistence between modern, affluent lifestyles and sustainable human prosperity.

In this Special Issue, on the topics of antimicrobials and the environment or antimicrobial-resistant bacteria and antimicrobials in the environment, intends to focus on broad environmental spaces, including rivers, lakes, marine areas, water treatment plants, wastewater treatment plants, and animal and livestock facilities. We invite research papers on the current situations of occurrence and dynamics, and purification methods that could be effective for reducing or mitigating human and animal health risks. This Special Issue also calls for review articles that propose the development of analytical methods based on novel approaches, summarize past research cases, and propose future measures to combat antimicrobial-resistant bacteria through the one health approach.

Dr. Takashi Azuma
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance (AMR)
  • antimicrobials
  • water purification plant (WTP)
  • wastewater treatment plant (WWTP)
  • hospital wastewater
  • livestock environment
  • aquaculture farm environment
  • aquatic environment

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

13 pages, 2068 KiB  
Article
Inactivation of Bacteria and Residual Antimicrobials in Hospital Wastewater by Ozone Treatment
by Takashi Azuma, Miwa Katagiri, Tsuyoshi Sekizuka, Makoto Kuroda and Manabu Watanabe
Antibiotics 2022, 11(7), 862; https://doi.org/10.3390/antibiotics11070862 - 27 Jun 2022
Cited by 8 | Viewed by 2892
Abstract
The emergence and spread of antimicrobial resistance (AMR) has become a persistent problem globally. In this study, an ozone treatment facility was established for an advanced hospital wastewater treatment in a core hospital facility in an urban area in Japan to evaluate the [...] Read more.
The emergence and spread of antimicrobial resistance (AMR) has become a persistent problem globally. In this study, an ozone treatment facility was established for an advanced hospital wastewater treatment in a core hospital facility in an urban area in Japan to evaluate the inactivation of antimicrobial-resistant bacteria and antimicrobials. Metagenomic DNA-seq analysis and the isolation of potential extended-spectrum β-lactamase (ESBL)-producing bacteria suggested that ozone exposure for at least 20 min is required for the adequate inactivation of DNA and ESBL-producing bacteria. Escherichia coli and Klebsiella species were markedly susceptible to 20-min ozone exposure, whereas Raoultella ornithinolytica and Pseudomonas putida were isolated even after an 80-min exposure. These ozone-resistant bacteria might play a pivotal role as AMR reservoirs in the environment. Nine antimicrobials (ampicillin, cefdinir, cefpodoxime, ciprofloxacin, levofloxacin, clarithromycin, chlortetracycline, minocycline, and vancomycin) were detected at 373 ng/L to 27 μg/L in the hospital wastewater, and these were removed (96–100% removal) after a 40-min treatment. These results facilitate a comprehensive understanding of the AMR risk posed by hospital wastewater and provides insights for devising strategies to eliminate or mitigate the burden of antimicrobial-resistant bacteria and the flow of antimicrobials into the environment. To the best of our knowledge, this is the first report on the implementation of a batch-type, plant-scale ozone treatment system in a hospital facility to execute and evaluate the inactivation of drug-resistant bacteria and antimicrobials. Full article
(This article belongs to the Special Issue Antibiotics and Environment − Research and Development toward the One Health Approach)
►▼ Show Figures

Figure 1

Other

Jump to: Research

17 pages, 580 KiB  
Brief Report
A Universal LC-MS/MS Method for Simultaneous Detection of Antibiotic Residues in Animal and Environmental Samples
by Chak-Lun Chan, Hogan Kok-Fung Wai, Peng Wu, Siu-Wai Lai, Olivia Sinn-Kay Chan and Hein M. Tun
Antibiotics 2022, 11(7), 845; https://doi.org/10.3390/antibiotics11070845 - 24 Jun 2022
Cited by 15 | Viewed by 3900
Abstract
Detecting and monitoring the usage of antibiotics is a critical aspect of efforts to combat antimicrobial resistance. Antibiotic residue testing with existing LC-MS/MS methods is limited in detection range. Current methods also lack the capacity to detect multiple antibiotic residues in different samples [...] Read more.
Detecting and monitoring the usage of antibiotics is a critical aspect of efforts to combat antimicrobial resistance. Antibiotic residue testing with existing LC-MS/MS methods is limited in detection range. Current methods also lack the capacity to detect multiple antibiotic residues in different samples simultaneously. In this study, we demonstrate a methodology that permits simultaneous extraction and detection of antibiotic residues in animal and environmental samples. A total of 30 different antibiotics from 13 classes could be qualitatively detected with our methodology. Further study to reduce analytes’ matrix effect would allow for quantification of antibiotic residues. Full article
(This article belongs to the Special Issue Antibiotics and Environment − Research and Development toward the One Health Approach)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop