Optimizing Antibiotics Therapy for Combating Difficult-to-Treat Infections by Multidrug-Resistant Gram-Negative Bacteria

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiotic Therapy in Infectious Diseases".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 128

Special Issue Editor

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Guest Editor
IRCCS Azienda Ospedaliera, Universitaria di Bologna, Policlinico di S.Orsola, Bologna, Italy
Interests: antimicrobial resistance; genomic analysis; molecular epidemiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Infections due to multidrug-resistant Gram-negative bacteria represent a formidable hurdle in the treatment landscape and are a leading cause of illness and mortality, especially among critically ill patients. Gram-negative bacteria are responsible for many infections, including urinary tract, pneumonia, bloodstream, and intra-abdominal infections. In recent years, the adaptability of the Gram-negative bacteria and the emerging multidrug resistance have been one of the most urgent threats in the healthcare system and a challenge for clinicians. These challenges impact the ability to successfully treat bacterial infections and contribute to the global issue of antibiotic resistance. In response to this urgent need, we announce this Special Issue, inviting contributions from researchers at the forefront of microbiology, pharmacology, and clinical medicine. This Special Issue aims to assemble cutting-edge research that optimizes antibiotic strategies to effectively combat infections caused by these challenging pathogens.

Dr. Paolo Gaibani
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • antibiotics therapy
  • Gram-negative bacteria
  • multidrug resistance
  • bacterial infection
  • healthcare system 

Published Papers

This special issue is now open for submission.
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