Methods for Prevent Biofilm Formation and Treat the Infections Caused by Biofilm Formed on Biotics or Abiotic Surfaces

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiofilm Strategies".

Deadline for manuscript submissions: 31 May 2024 | Viewed by 1347

Special Issue Editors


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Guest Editor
Department of Dental Materials and Prostheses, School of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo 14040-904, Brazil
Interests: biofilm in dental prosthesis; dental prosthesis sanitizers; maxillofacial prosthesis; acrylic resin; silicone
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Dental Materials and Prostheses, School of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo 14040-904, Brazil
Interests: oral health maintenance; conventional and implant-retained dental prostheses; clinical dentistry with local and systemic implications
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biofilms are complex structures formed by communities of microorganisms adhered to a biotic or abiotic surface surrounded by an extracellular matrix consisting of polysaccharides, proteins and extracellular DNA. In biofilm form, microorganisms are less sensitive to antibiotics than in planktonic form. Variations in the concentration of antibiotics throughout a biofilm cause the exposure of microbial cells to levels below inhibitory concentrations, and this can cause resistance in microorganisms. To avoid infections, the ideal is to promote the removal of biofilm daily. However, when there is an established infection, the ideal would be to disorganize the biofilm so that the antibiotic can reach microbial cells in the necessary concentration. Thus, the objective is to compile a Special Edition with studies that propose methods for preventing the formation of biofilm and/or that promote the disruption of the biofilm concomitant with the application of an antibiotic for the treatment of infections.

Prof. Dr. Cláudia Helena Silva-Lovato
Dr. Adriana Barbosa Ribeiro
Guest Editors

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Keywords

  • biofilms
  • infection
  • prevention
  • treatment

Published Papers (1 paper)

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Research

15 pages, 703 KiB  
Article
Effect of Hygiene Protocols on the Mechanical and Physical Properties of Two 3D-Printed Denture Resins Characterized by Extrinsic Pigmentation as Well as the Mixed Biofilm Formed on the Surface
by Adriana Barbosa Ribeiro, Beatriz Marcatto Tinelli, Lorena Mosconi Clemente, Beatriz de Camargo Poker, Viviane de Cássia Oliveira, Evandro Watanabe and Cláudia Helena Silva-Lovato
Antibiotics 2023, 12(11), 1630; https://doi.org/10.3390/antibiotics12111630 - 17 Nov 2023
Cited by 1 | Viewed by 1090
Abstract
To assess the effect of hygiene protocols and time on the physical–mechanical properties and colony-forming units (CFU) of Candida albicans, Staphylococcus aureus, and Streptococcus mutans on 3D-printed denture resins (SmartPrint and Yller) with extrinsic pigmentation compared to conventional resin (CR). The [...] Read more.
To assess the effect of hygiene protocols and time on the physical–mechanical properties and colony-forming units (CFU) of Candida albicans, Staphylococcus aureus, and Streptococcus mutans on 3D-printed denture resins (SmartPrint and Yller) with extrinsic pigmentation compared to conventional resin (CR). The protocols were evaluated: brushing (B), brushing and immersion in water (W), 0.25% sodium hypochlorite (SH), and 0.15% triclosan (T), simulating 0, 1, 3, and 5 years. The data were analyzed by ANOVA with repeated measurements, ANOVA (Three-way) and Tukey’s post-test, generalized linear model with Bonferroni adjustment, and ANOVA (Two-way) and Tukey’s post-test (α = 0.05). The protocols influenced color (p = 0.036) and Knoop hardness (p < 0.001). Surface roughness was influenced by protocols/resin (p < 0.001) and time/resin (p = 0.001), and flexural strength by time/protocols (p = 0.014). C. albicans showed interactions with all factors (p = 0.033). Staphylococcus aureus was affected by protocols (p < 0.001). Streptococcus mutans exhibited no count for SH and T (p < 0.001). Yller resin showed more color changes. The 3D-printed resins displayed lower microhardness, increased roughness, and decreased flexural strength compared to CR with all protocols in a simulated period of 5 years. The indication of printed resins should be restricted to less than 3 years. Full article
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