Reprint

Genetics and Epigenetics in Complex Diseases

Edited by
June 2023
238 pages
  • ISBN978-3-0365-7857-6 (Hardback)
  • ISBN978-3-0365-7856-9 (PDF)

This book is a reprint of the Special Issue Genetics and Epigenetics in Complex Diseases that was published in

Biology & Life Sciences
Chemistry & Materials Science
Medicine & Pharmacology
Summary

Many of the most common diseases are influenced by a combination of multiple factors, which include environmental effectors as well as genetic and epigenetic variations. Therefore, these diseases are grouped under the term “complex” diseases because, from the point of view of genetics, they cannot be explained by simple Mendelian inheritance. The aim of this special issue was to identify genetic and epigenetic factors involved in such diseases in order to improve not only the knowledge of risk factors for those diseases, which could be of help for prevention, but also the understanding and characterization of each disease and to optimize and personalize the treatment.

Format
  • Hardback
License
© by the authors
Keywords
chromatin remodeling; circular RNA; DNA methylation; histone modification; non-coding RNA; oncogenes; tumor suppressor genes; tumor virus; chronic lymphocytic leukemia; CLL; DNA methylation; SF3B1 mutation; NOTCH; IKAROS; syncope; vasovagal syncope; genetics; complex disorders; susceptibility; twin studies; family studies; candidate gene association studies; genome-wide studies; acute myeloid leukemia; pediatric; trio sequencing; germline cancer predisposition; POT1; shelterin complex; psoriasis; psoriatic arthritis; NF-κB; comorbidities; genetic architecture; SKP1; CUL1; RBX1; SKP2; FBXW7; FBXO5; SCF complex; genome instability; chromosome instability; cancer; VDBP; vitamin D binding protein; rs7041; rs4588; bone density; diabetes; obesity; COPD; pulmonary tuberculosis; SNP; MD; PD; CD33; Alzheimer’s disease; sialic acid; phagocytosis; KLF14; body shape indices; metabolic traits; differential effect; genetic variants; DNA methylation; resistin; soluble suppression of tumorigenicity 2; weighted genetic risk score; Taiwan Biobank; coronary artery disease; all-cause mortality; major adverse cardiac events; acute lymphoblastic leukemia; trio sequencing; germline cancer predisposition; RAD21; cohesin complex; n/a