Analytical Techniques in Pharmaceutical and Biomedical Analysis

doi:10.3390/books978-3-0365-7025-9

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Analytical Techniques in Pharmaceutical and Biomedical Analysis

Edited by

March 2023

350 pages

ISBN978-3-0365-7024-2 (Hardback)
ISBN978-3-0365-7025-9 (PDF)

https://doi.org/10.3390/books978-3-0365-7025-9

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This book is a reprint of the Special Issue Analytical Techniques in Pharmaceutical and Biomedical Analysis that was published in

Chemistry & Materials Science

Medicine & Pharmacology

Summary

This Special Issue is a collection of research topics on developing analytical and bioanalytical methods for isolation, identification, and determination of substances in biomedical and pharmaceutical matrices. Special attention is given to advancements in sample preparation, separation techniques and novel detection methods of small molecules, peptides, and monoclonal antibodies. The presented analytical methods exhibit several applications, including pharmacokinetic studies, therapeutic drug monitoring, microdialysis, toxicology, disease screening or drug stability study. Two comprehensive review articles were also presented on applying capillary electrophoresis to analyze bioactive compounds in herbal matrices.

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Keywords

CNS; sulfasalazine; brain to plasma ratio; LC-ESI-TOF-MS; rituximab; quadripolar mass spectrometer; albumin depletion; pharmacokinetics; orbitrap mass spectrometer; IgG-immunocapture; bubble-generating magnetic liposomes; bionic membrane; permeable compounds; herbal medicines; LC–MS; capillary electrophoresis; herbal; raw material; tea; polyphenols; flavonoids; amino acids; coumarins; alkaloids; chlorambucil and valproic acid; HPLC-UV and GC-MS methods; optimization and validation; determination in plasma; combined anticancer therapy; capillary electrophoresis; herbal drugs; medicinal plants; quality control; quantitative analysis; pharmaceutical analysis; 4-acetamidobenzoic acid; validation; pharmacokinetic; pigs; LC-MS/MS; pharmaceutical analysis; iron determination; spectrophotometry; flow analysis; direct injection detector; multi-pumping flow system; medical errors; hospital workflow; patient safety; Raman spectroscopy; IV drugs; piperacillin; tazobactam; non-invasively; vildagliptin; remogliflozin; ratio derivative spectrophotometry; determination; formulation; ecofriendly; confidence interval; stability; retrospective analysis; sample size; regulatory bioanalysis; bioanalytical method validation; heparin; metal–organic framework; zeolite imidazolate framework-8; kinetic; thermodynamic; Oncheong-eum; traditional herbal prescription; method development; method validation; high-performance liquid chromatography; thalassemia; human hemoglobin; wooden-tip electrospray ionization; multiply charged ions; mass spectrometry; multiply charged ion; GC–MS; analytical QbD; genotoxic impurity; alkyl halide; (Q)SAR; analytical method development; tyrosine kinase inhibitor; liquid chromatography–mass spectrometry; active metabolite; therapeutic drug monitoring; chronic lymphocytic leukemia; assay error equation; oral anticancer drug; IWR-1-endo; Wnt signaling inhibitor; LC-MS/MS; solid-phase extraction; pharmacokinetics; cerebral microdialysis; bioanalysis; Tafamidis; polymorphs; crystal structure; powder diffraction; thermal stability; blood collection tubes; citrate anticoagulant; direct spectrometric determination; quality control method; anticoagulant concentration; draw volume; anticoagulant volume; magnesium contamination; potassium contamination; Agrimonia pilosa; apigenin-7-O-glucuronide; cream; HPLC-DAD; validation