Reprint

Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non Communicable Diseases II

Edited by
June 2022
224 pages
  • ISBN978-3-0365-4363-5 (Hardback)
  • ISBN978-3-0365-4364-2 (PDF)

This book is a reprint of the Special Issue Oxidative Stress and Inflammation as Targets for Novel Preventive and Therapeutic Approaches in Non Communicable Diseases II that was published in

Biology & Life Sciences
Summary

Non-communicable diseases are chronic non-infectious pathologies that represent the leading cause of death and disability for the general population. Oxidative stress and inflammation induce and modulate several signaling pathways that play a crucial role in the pathophysiology and progression of these diseases. Therefore, they represent a good target for the development of different therapeutic strategies and open new strategies for assessment and intervention.

This book focuses on different approaches to investigate the underlying pathogenesis and treatment mechanisms of conditions related to oxidative stress and inflammation. Particular attention is given to biomarkers specific to these features that can detail the pathogenesis and evolution of kidney disease, cardiovascular disease, obesity, breast cancer, and idiopathic pulmonary fibrosis. In addition, the potential medicinal and beneficial effects of plant compounds such as oleuropein, columbianadin, and rebaudioside A are addressed.

Format
  • Hardback
License
© by the authors
Keywords
Crohn’s disease; oxidative stress; antioxidants; pathogenesis; inflammation; microbiota; dysbiosis; environmental factors; epigenetics; C. elegans; non-nutritive sweetener; rebaudioside A; aging; oxidative stress resistance; TOR; lipidomics; columbianadin; LPS; hydroxyl radicals; HO-1 expression; liver-injury; NF-κB/MAPK signaling pathways; brain edema; hemorrhagic stroke; intracranial pressure; kidney dysfunction; stress hormones; chronic kidney disease; oxidative stress; polymorphonuclear leukocytes; mononuclear leukocytes; hemodialysis; peritoneal dialysis; diabetes; nephropathy; epigenetics; histone acetylation; p300/CBP; NADPH oxidase; oxidative stress; redox-signalling; p47phox; knockout mice; Angiotensin II; cardiac hypertrophy; apoptosis; obesity-related inflammation; oxidative stress; mitochondrial biogenesis; mitochondrial dynamics; epithelial-to-mesenchymal transition (EMT); estrogen receptor beta (ERβ); breast cancer; oleuropein; colon tumours; PIRC rats; activated macrophages; chronic inflammation; inducible nitric oxide synthetase (iNOS); cyclooxygenase-2 (COX-2); nitric oxide (NO); hyponatremia; osmotic stress; oxidative stress; ROS; senescence; cancer; osteoporosis; neuronal cells homeostasis; angiotensin II type 1 receptor (AT1R); hypertension; heterodimer; toll like receptor 4; nucleus tractus solitarii; opioids; idiopathic pulmonary fibrosis; NADPH oxidase; NOX4; di-tyrosine; immunohistochemistry; human lung tissue; n/a