Reprint

Hybrid Modelling and Multi- Parametric Control of Bioprocesses

Edited by
February 2018
148 pages
  • ISBN978-3-03842-745-2 (Paperback)
  • ISBN978-3-03842-746-9 (PDF)

This book is a reprint of the Special Issue Hybrid Modelling and Multi-Parametric Control of Bioprocesses that was published in

Biology & Life Sciences
Engineering
Format
  • Paperback
License
© 2018 by the authors; CC BY-NC-ND license
Keywords
E. coli SHuffle® T7; Glycosyltransferase GalNAcT2; In Situ monitoring; soft sensor; fluorescence spectroscopy; multivariate curve resolution; E. coli; fed-batch; fermentation; carbon mass balance constraint; soft constraints; alternating least squares; hybrid modelling; State estimation; hybrid modeling; Unscented Kalman Filter; recombinant protein production; computational fluid dynamics; cell cycle model; Lagrange trajectory; scale-up; stirred tank reactor; population dynamics; energy level; mesenchymal stem cells; scaffold-free; aggregate cultivation; stirred tank reactor; dynamic cultivation; hypoxia; stemness; computational fluid dynamics; perfusion bioreactor system; 3D cell culture; dynamic cultivation; fluid shear stress; computational fluid dynamics; antibody aggregation; ANS; bioprocess monitoring; Bis-ANS; fluorescence spectroscopy; CHO; retrospective power analysis; process characterization study; process validation stage 1; criticality assessment; control strategy; design of experiments; process validation; process characterization study; holistic process model; predict out of specification events; Monte Carlo simulation; biopharmaceutical manufacturing; E. coli; mixed feed system; glycerol; recombinant proteins; bioprocess engineering