Reprint

The Amazing World of IDPs in Human Diseases II

Edited by
April 2022
130 pages
  • ISBN978-3-0365-3107-6 (Hardback)
  • ISBN978-3-0365-3106-9 (PDF)

This book is a reprint of the Special Issue The Amazing World of IDPs in Human Diseases II that was published in

Biology & Life Sciences
Medicine & Pharmacology
Summary

This Special Issue includes seven full articles from more than 35 scientists from all around the world working in the amazing field of IDPs. The collected papers unveil novel aspects related to the wide world of IDPs. Using a variety of methods including biochemical, spectroscopic and computational techniques, they represent a step forward in the study and characterization of many IDPs involved in human diseases, with a focus on conformational features, environmental effects, recognition mechanisms and targeting. 

Format
  • Hardback
License
© by the authors
Keywords
intrinsically disordered protein (IDP); prostate apoptosis response-4 (Par-4); tumor suppressor; circular dichroism (CD) spectroscopy; dynamic light scattering (DLS); aggregation; coiled-coil; caspase; α-helix; amyloid; β-sheet; hydration; intrinsically disordered proteins; oligomer; protein–protein interactions; wide-line 1H NMR; apoptosis; cancer; longevity; FOXO3; local compaction tool; intrinsically disordered protein; DNA-binding; transcription factor; molecular dynamics simulation; computational biology; MeCP2; intrinsically disordered proteins; structural stability; thermal and chemical denaturation; differential scanning calorimetry; respiratory syncytial virus; phosphoprotein; nuclear magnetic resonance; tetramerization domain; transient secondary structure; protein dynamics; intrinsically disordered proteins; nuclear protein 1; drug discovery; ligand-based design; isothermal titration calorimetry; biological assays; α-synuclein; glycation; DJ-1; Parkinson’s disease; protein–protein interactions; nuclear magnetic resonance spectroscopy; atomic force microscopy; n/a