Reprint

Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen

Edited by
January 2021
232 pages
  • ISBN978-3-03943-376-6 (Hardback)
  • ISBN978-3-03943-377-3 (PDF)

This book is a reprint of the Special Issue Aggregatibacter actinomycetemcomitans—Gram-Negative Bacterial Pathogen that was published in

Biology & Life Sciences
Medicine & Pharmacology
Public Health & Healthcare
Summary

Aggregatibacter actinomycetemcomitans is a well-studied Gram-negative bacterium that can often be found in the oral cavity of young individuals. It has several virulence factors and a large genetic diversity, which results in both harmless and highly virulent genotypes. To determine the virulence potential of the isolated bacteria, genetic profiling is recommended. Advanced knowledge of the virulence mechanisms induced by this bacterium is important for the development of future personalized preventive and treatment strategies. The fifteen papers in this book provide a strong and relevant background that can contribute to the improvement of future diagnosis and research strategies.

Format
  • Hardback
License
© 2022 by the authors
Keywords
Aggregatibacter actinomycetemcomitans; cagE; virB1; virB4; genotype; virulence; mRNA assay; quantitative ELISA; cell lysis assay; leukotoxin; JP2 genotype; Aggregatibacter actinomycetemcomitans; leukotoxin; cytolethal distending toxin; lipopolysaccharides; cytokine binding factors; horizontal gene transfer; outer membrane vesicles; biofilm; proteomic; adherence; endocarditis; fimbriae; JP2; leukotoxin; periodontitis; taxonomy; core and accessory genes; average nucleotide identity; principal component analysis; Aggregatibacter actinomycetemcomitans; keratins; organotypic gingival mucosa; A. actinomycetemcomitans; RNA-Seq; genomic islands; core genes; accessory genes; stress; nutrient limitation; differentially expressed genes.; Aggregatibacter actinomycetemcomitans; cytolethal distending toxin; lymphocytes; apoptosis; virulence; Aggregatibacter actinomycetemcomitans; RTX toxin; localized aggressive periodontitis; LFA-1; leukotoxin (LtxA); endocytosis; n/a; JP2 clone of Aggregatibacter actinomycetemcomitans; periodontitis; JP2 in Caucasian; microbiological diagnosis; adjunctive antibiotics; Aggregatibacter actinomycetemcomitans; leukotoxin; localized aggressive periodontitis: animal studies: human studies; landscape ecology; damage/response framework; bacteremia; horseshoe crab; Aggregatibacter actinomycetemcomitans; periodontitis; Origanum vulgare; essential oil; antimicrobial activity; minimum inhibitory concentration; minimal bactericidal concentration; cytotoxicity; leukotoxin neutralization; A. actinomycetemcomitans; inflammasome; immune response; periodontal disease; Aggregatibacter actinomycetemcomitans; leukotoxin; cytolethal distending toxin; lipopolysaccharides; cytokine binding factors; horizontal gene transfer; outer membrane vesicles; biofilm; proteomics