2 June 2023
Brain Sciences | Highly Cited Papers in 2021 in the Section “Neurodegenerative Diseases”

The “Neurodegenerative Diseases” Section aims to publish articles on amyotrophic lateral sclerosis, multiple sclerosis, Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple system atrophy, prion diseases, etc.

As all of the articles published in our journal are of an open access format, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2021 listed below:

1. “Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease: Current Evidence and Future Perspectives”
by Donovan A. McGrowder, Fabian Miller, Kurt Vaz, Chukwuemeka Nwokocha, Cameil Wilson-Clarke, Melisa Anderson-Cross, Jabari Brown, Lennox Anderson-Jackson, Lowen Williams, Lyndon Latore et al.
Brain Sci. 2021, 11(2), 215; https://doi.org/10.3390/brainsci11020215
Available online: https://www.mdpi.com/2076-3425/11/2/215

2. “One Year Trajectory of Caregiver Burden in Parkinson’s Disease and Analysis of Gender-Specific Aspects”
by Martin Klietz, Hannah von Eichel, Theresa Schnur, Selma Staege, Günter U. Höglinger, Florian Wegner and Stephanie Stiel
Brain Sci. 2021, 11(3), 295; https://doi.org/10.3390/brainsci11030295
Available online: https://www.mdpi.com/2076-3425/11/3/295

3. “Informal Caregiving in Amyotrophic Lateral Sclerosis (ALS): A High Caregiver Burden and Drastic Consequences on Caregivers’ Lives”
by Pavel Schischlevskij, Isabell Cordts, René Günther, Benjamin Stolte, Daniel Zeller, Carsten Schröter, Ute Weyen, Martin Regensburger, Joachim Wolf, Ilka Schneider et al.
Brain Sci. 2021, 11(6), 748; https://doi.org/10.3390/brainsci11060748
Available online: https://www.mdpi.com/2076-3425/11/6/748

4. “Cerebrospinal Fluid α-Synuclein Species in Cognitive and Movements Disorders”
by Vasilios C. Constantinides, Nour K. Majbour, George P. Paraskevas, Ilham Abdi, Bared Safieh-Garabedian, Leonidas Stefanis, Omar M. El-Agnaf and Elisabeth Kapaki
Brain Sci. 2021, 11(1), 119; https://doi.org/10.3390/brainsci11010119
Available online: https://www.mdpi.com/2076-3425/11/1/119

5. “Blood Biomarkers in Frontotemporal Dementia: Review and Meta-Analysis”
by Sofia Ntymenou, Ioanna Tsantzali, Theodosis Kalamatianos, Konstantinos I. Voumvourakis, Elisabeth Kapaki, Georgios Tsivgoulis, George Stranjalis and George P. Paraskevas
Brain Sci. 2021, 11(2), 244; https://doi.org/10.3390/brainsci11020244
Available online: https://www.mdpi.com/2076-3425/11/2/244

6. “Proteomic Profile of Saliva in Parkinson’s Disease Patients: A Proof of Concept Study”
by Monika Figura, Ewa Sitkiewicz, Bianka Świderska, Łukasz Milanowski, Stanisław Szlufik, Dariusz Koziorowski and Andrzej Friedman
Brain Sci. 2021, 11(5), 661; https://doi.org/10.3390/brainsci11050661
Available online: https://www.mdpi.com/2076-3425/11/5/661

7. “Relationship Satisfaction in People with Parkinson’s Disease and Their Caregivers: A Cross-Sectional Observational Study”
by Johanne Heine, Hannah von Eichel, Selma Staege, Günter U. Höglinger, Florian Wegner and Martin Klietz
Brain Sci. 2021, 11(6), 822; https://doi.org/10.3390/brainsci11060822
Available online: https://www.mdpi.com/2076-3425/11/6/822

8. “Informal Caregivers in Amyotrophic Lateral Sclerosis: A Multi-Centre, Exploratory Study of Burden and Difficulties”
by Éilís Conroy, Polly Kennedy, Mark Heverin, Iracema Leroi, Emily Mayberry, Anita Beelen, Theocharis Stavroulakis, Leonard H. van den Berg, Christopher J. McDermott, Orla Hardiman et al.
Brain Sci. 2021, 11(8), 1094; https://doi.org/10.3390/brainsci11081094
Available online: https://www.mdpi.com/2076-3425/11/8/1094

9. “Understanding the Modulatory Effects of Cannabidiol on Alzheimer’s Disease”
by Yinyi Xiong and Chae-Seok Lim
Brain Sci. 2021, 11(9), 1211; https://doi.org/10.3390/brainsci11091211
Available online: https://www.mdpi.com/2076-3425/11/9/1211

10. “Analysis of Transition of Patients with Parkinson’s Disease into Institutional Care: A Retrospective Pilot Study”
by Ida Jensen, Emily Lescher, Stephanie Stiel, Florian Wegner, Günter Höglinger and Martin Klietz
Brain Sci. 2021, 11(11), 1470; https://doi.org/10.3390/brainsci11111470
Available online: https://www.mdpi.com/2076-3425/11/11/1470

11. “Connection Lost, MAM: Errors in ER–Mitochondria Connections in Neurodegenerative Diseases”
by Ashu Johri and Abhishek Chandra
Brain Sci. 2021, 11(11), 1437; https://doi.org/10.3390/brainsci11111437
Available online: https://www.mdpi.com/2076-3425/11/11/1437

12. “Another Perspective on Huntington’s Disease: Disease Burden in Family Members and Pre-Manifest HD When Compared to Genotype-Negative Participants from ENROLL-HD”
by Jannis Achenbach and Carsten Saft
Brain Sci. 2021, 11(12), 1621; https://doi.org/10.3390/brainsci11121621
Available online: https://www.mdpi.com/2076-3425/11/12/1621

13. “Predicting Conversion from MCI to AD Combining Multi-Modality Data and Based on Molecular Subtype”
by Hai-Tao Li, Shao-Xun Yuan, Jian-Sheng Wu, Yu Gu and Xiao Sun
Brain Sci. 2021, 11(6), 674; https://doi.org/10.3390/brainsci11060674
Available online: https://www.mdpi.com/2076-3425/11/6/674

14. “Non-Immersive Virtual Reality to Improve Balance and Reduce Risk of Falls in People Diagnosed with Parkinson’s Disease: A Systematic Review”
by Héctor García-López, Esteban Obrero-Gaitán, Adelaida María Castro-Sánchez, Inmaculada Carmen Lara-Palomo, Francisco Antonio Nieto-Escamez and Irene Cortés-Pérez
Brain Sci. 2021, 11(11), 1435; https://doi.org/10.3390/brainsci11111435
Available online: https://www.mdpi.com/2076-3425/11/11/1435

15. “A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats”
by Elina Rubin, Agnese C. Pippione, Matthew Boyko, Giacomo Einaudi, Stefano Sainas, Massimo Collino, Carlo Cifani, Marco L. Lolli, Naim Abu-Freha, Jacob Kaplanski et al.
Brain Sci. 2022, 12(1), 35; https://doi.org/10.3390/brainsci12010035
Available online: https://www.mdpi.com/2076-3425/12/1/35

16. “Genotyping and Plasma/Cerebrospinal Fluid Profiling of a Cohort of Frontotemporal Dementia–Amyotrophic Lateral Sclerosis Patients”
by Mara Bourbouli, George P. Paraskevas, Mihail Rentzos, Lambros Mathioudakis, Vasiliki Zouvelou, Anastasia Bougea, Athanasios Tychalas, Vasilios K. Kimiskidis, Vasilios Constantinides, Spiros Zafeiris et al.
Brain Sci. 2021, 11(9), 1239; https://doi.org/10.3390/brainsci11091239
Available online: https://www.mdpi.com/2076-3425/11/9/1239

17. “Caring for a Relative with Dementia: Determinants and Gender Differences of Caregiver Burden in the Rural Setting”
by Dagmar Schaffler-Schaden, Simon Krutter, Alexander Seymer, Roland Eßl-Maurer, Maria Flamm and Jürgen Osterbrink
Brain Sci. 2021, 11(11), 1511; https://doi.org/10.3390/brainsci11111511
Available online: https://www.mdpi.com/2076-3425/11/11/1511

18. “Unlike Brief Inhibition of Microglia Proliferation after Spinal Cord Injury, Long-Term Treatment Does Not Improve Motor Recovery”
by Gaëtan Poulen, Sylvain Bartolami, Harun N. Noristani, Florence E. Perrin and Yannick N. Gerber
Brain Sci. 2021, 11(12), 1643; https://doi.org/10.3390/brainsci11121643
Available online: https://www.mdpi.com/2076-3425/11/12/1643

19. “Psychological Impact of Parkinson Disease Delusions on Spouse Caregivers: A Qualitative Study”
by Caroline J. Deutsch, Noelle Robertson and Janis M. Miyasaki
Brain Sci. 2021, 11(7), 871; https://doi.org/10.3390/brainsci11070871
Available online: https://www.mdpi.com/2076-3425/11/7/871

20. “Early Spatial Memory Impairment in a Double Transgenic Model of Alzheimer’s Disease TgF-344 AD”
by Stephanie L. Proskauer Pena, Konstantinos Mallouppas, Andre M. G. Oliveira, Frantisek Zitricky, Athira Nataraj and Karel Jezek
Brain Sci. 2021, 11(10), 1300; https://doi.org/10.3390/brainsci11101300
Available online: https://www.mdpi.com/2076-3425/11/10/1300

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