On 15 June 2023, MDPI and Cells (ISSN: 2073-4409) organized a webinar on cells, titled Systems Biology of Apoptotic and Non-apoptotic Signaling. The webinar focused on contemporary views on the intricate crosstalk of apoptotic and non-apoptotic networks in cell-regulating life/death decisions.

Life/death decisions in a cell are regulated by the balance between apoptotic and non-apoptotic signaling pathways. Although these pathways have been studied relatively well, their quantitative regulation has, until recently, been poorly understood. In this regard, the construction of mathematical models of apoptotic and non-apoptotic signaling pathways led to enormous progress in the quantitative understanding of cell fate control. Prof. Dr. Inna Lavrik first dissected the quantitative regulation of cell fate decisions in death receptor networks. Then, Prof. Boris Zhivotovsky showed us programmed cell death in the past, present, and future. Finally, Prof. Olga Lavrik presented poly(ADP-ribose)polymerases as dynamic triggers for biomolecular condensate formation. The three scholars comprehensively discussed the contemporary view on the intricate crosstalk of apoptotic and non-apoptotic networks in the cell regulating life/death decisions.

Please note that this webinar is associated with a Special Issue in Cells, “Systems Biology of Apoptotic and Non-apoptotic Signaling”. The deadline is 30 September 2023.

You can watch the recorded webinar at the following link: https://www.youtube.com/watch?v=ntLxD-eL8_A.

Webinar Chair and Keynote Speakers:

• Prof. Dr. Inna Lavrik, Translational Inflammation Research, Medical Faculty, Center of Dynamic Systems, Otto von Guericke University Magdeburg, Magdeburg, Germany;
• Prof. Boris Zhivotovsky, Institute of Environmental Medicine, Division of Toxicology, Karolinska Institute, Solna, Sweden;
• Prof. Olga Lavrik, Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia.