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Liposomal Supramolecular Strustures Based on the Antiviral Active Nanomaterials †

Institute of Semiconductor Physics, National Academy of Sciences of Ukraine, Prospect Nauky, 41, 03039 Kyiv, Ukraine
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Acad. Zabolotny Str, 154, 03680 Kyiv, Ukraine
Author to whom correspondence should be addressed.
Presented at the 2nd International Electronic Conference on Biomolecules: Biomacromolecules and the Modern World Challenges, 1–15 November 2022; Available online:
Biol. Life Sci. Forum 2022, 20(1), 18;
Published: 1 November 2022
Liposomal supramolecular strustures (SMS) are widespread in different areas of modern science. Due to their unique, multifaceted, and flexible properties, nanomaterials circumvent many challenges in diverse fields of medicine, including health, diagnosis, and treatment nanoliposomes being one of the most widely used nanoparticles in biomedicine [1]. Liposomes have been considered promising and versatile drug vesicles. Compared with traditional drug delivery systems, liposomes exhibit better properties, including site-targeting, sustained or controlled release, protection of drugs from degradation and clearance, superior therapeutic effects, and lower toxic side effects [2]. All these advantages are important for the development of efficient antiviral drugs which is one of the topical problems in modern virology.
Polysaccharides extracted from mushrooms have received growing attention in biomedical application [3]. They exhibit many biological activities including immune regulation, antioxidant and anti-inflammatory actions, antivirus, antitumor, and so on. Increasing advances in nanotechnology and nanoscience have raised great hopes in the field of biomedicine.
To deliver polysaccharide glucuronoxylomannan (GXM) extracted from the yellow brain mushroom Tremella mesenterica to sites of action, liposomes have been used as specific targeted systems. For the investigation of the impact of GMX containing SMS on the functionality of the tobacco mosaic virus surface plasmon resonance method was used. These have been found to improve the bioavailability of GXM polysaccharide and enhance their pharmacodynamic action.

Supplementary Materials

The presentation material of this work is available online at

Author Contributions

Conceptualization, O.K. and V.V.; methodology, B.S.; software, S.K.; validation, P.B. and S.K.; formal analysis, B.S.; investigation, P.B.; resources, O.K.; data curation, B.S.; writing—original draft preparation, P.B.; writing—review and editing, S.K.; visualization, B.S.; supervision, O.K.; project administration, O.K. All authors have read and agreed to the published version of the manuscript.


This research received no external funding.

Institutional Review Board Statement

Not applicable.

Informed Consent Statement

Not applicable.

Data Availability Statement

Not applicable.

Conflicts of Interest

The authors declare no conflict of interest.


  1. Nakhaei, P.; Margiana, R.; Bokov, D.O.; Abdelbasset, W.K.; Jadidi Kouhbanani, M.A.; Varma, R.S.; Marofi, F.; Jarahian, M.; Beheshtkhoo, N. Liposomes: Structure, Biomedical Applications, and Stability Parameters With Emphasis on Cholesterol. Front. Bioeng. Biotechnol. 2021, 9, 705886. [Google Scholar] [CrossRef] [PubMed]
  2. Liu, P.; Chen, G.; Zhang, J. A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives. Molecules 2022, 27, 1372. [Google Scholar] [CrossRef] [PubMed]
  3. Friedman, M. Mushroom Polysaccharides: Chemistry and Antiobesity, Antidiabetes, Anticancer, and Antibiotic Properties in Cells, Rodents, and Humans. Foods 2016, 5, 80. [Google Scholar] [CrossRef] [PubMed][Green Version]
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MDPI and ACS Style

Boltovets, P.; Kravchenko, S.; Vassilliev, V.; Kovalenko, O.; Snopok, B. Liposomal Supramolecular Strustures Based on the Antiviral Active Nanomaterials. Biol. Life Sci. Forum 2022, 20, 18.

AMA Style

Boltovets P, Kravchenko S, Vassilliev V, Kovalenko O, Snopok B. Liposomal Supramolecular Strustures Based on the Antiviral Active Nanomaterials. Biology and Life Sciences Forum. 2022; 20(1):18.

Chicago/Turabian Style

Boltovets, Praskoviya, Sergii Kravchenko, Volodymyr Vassilliev, Oleksiy Kovalenko, and Borys Snopok. 2022. "Liposomal Supramolecular Strustures Based on the Antiviral Active Nanomaterials" Biology and Life Sciences Forum 20, no. 1: 18.

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