Next Issue
Volume 86, January
Previous Issue
Volume 86, September
 
 
arm-logo

Journal Browser

Journal Browser
Advances in Respiratory Medicine is published by MDPI from Volume 90 Issue 4 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Via Medica.

Adv. Respir. Med., Volume 87, Issue 4 (August 2019) – 11 articles , Pages 203-256

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Select all
Export citation of selected articles as:
255 KiB  
Case Report
A Huge Fishhook in the Right Main Bronchus
by Ioannis Pantazopoulos and Xristoyla Petraki
Adv. Respir. Med. 2019, 87(4), 254; https://doi.org/10.5603/ARM.2019.0038 - 30 Aug 2019
Cited by 2 | Viewed by 349
Abstract
A 58-year-old male patient with no previous medical history presented to the emergency department with a non-productive cough and hemoptysis [...] Full article
177 KiB  
Case Report
Pulmonary Tuberculosis in a Male with Sarcoidosis
by Marcin Skowroński, Anna Halicka and Aleksander Barinow-Wojewódzki
Adv. Respir. Med. 2019, 87(4), 252-253; https://doi.org/10.5603/ARM.2019.0043 - 30 Aug 2019
Viewed by 357
Abstract
A 45-year-old nonsmoking male patient was admitted with a nonproductive cough. He was in the follow-up for sarcoidosis stage II for 2 years [...] Full article
540 KiB  
Case Report
An Unusual Case of Idiopathic Inflammatory Myopathy Presenting with Organizing Pneumonia as Cavitary Lesions
by Sumita Agrawal, Nitesh Gupta, Rohit Kumar, M. K. Sen, Shibdas Chakrabarti and Jagdish Chander Suri
Adv. Respir. Med. 2019, 87(4), 243-246; https://doi.org/10.5603/ARM.2019.0041 - 30 Aug 2019
Cited by 2 | Viewed by 369
Abstract
A young woman presented with gradually progressive breathlessness, cough and muscle weakness for one and a half year. Her chest radiograph showed multiple, bilateral thin-walled cavitary lesions. Her serum was found to be positive for anti-Jo1 antibodies on serology. Histopathology of lung lesions [...] Read more.
A young woman presented with gradually progressive breathlessness, cough and muscle weakness for one and a half year. Her chest radiograph showed multiple, bilateral thin-walled cavitary lesions. Her serum was found to be positive for anti-Jo1 antibodies on serology. Histopathology of lung lesions was suggestive of organizing pneumonia. The muscle biopsy demonstrated a myopathic pattern. On the basis of these findings she was diagnosed to be the case of idiopathic inflammatory myopathy. Her condition improved significantly after treatment with steroids. Full article
161 KiB  
Review
Disseminated Bacille Calmette-Guérin Infection at a Glance: A Mini Review of the Literature
by Maryam Hassanzad, Ali Valinejadi, Sepideh Darougar, Seyed Karen Hashemitari and Ali Akbar Velayati
Adv. Respir. Med. 2019, 87(4), 239-242; https://doi.org/10.5603/ARM.2019.0040 - 30 Aug 2019
Cited by 13 | Viewed by 553
Abstract
Introduction: Immunodeficient children are at a high risk of disseminated Bacillus Calmette-Guérin [BCG] infection. We assessed the literature on clinical manifestations of BCGosis in children with specific primary immunodeficiencies. Material and methods: We conducted a systematic review of clinical practice articles by searching [...] Read more.
Introduction: Immunodeficient children are at a high risk of disseminated Bacillus Calmette-Guérin [BCG] infection. We assessed the literature on clinical manifestations of BCGosis in children with specific primary immunodeficiencies. Material and methods: We conducted a systematic review of clinical practice articles by searching Medline, PubMed, Embase, Scopus, Web of Science and Google Scholar from their inception to date. Results: Thirty-seven articles were included regarding BCG vaccination and its dissemination in children with primary immunodeficiencies. Articles on dissemination after intravesicular BCG were excluded from the study. Conclusions: Since disseminated BCG vaccination may be the first manifestation of a primary immunodeficiency disease, a comprehensive search for immunological defects in children developing these problems after BCG vaccination seems rational. Full article
1890 KiB  
Article
The TNF-α, P53 Protein Response and Lung Respiratory Changes Related to Exercise, Chronic Hypoxia and Adiantum capillus-Veneris Supplementation
by Mehdi Yadegari, Simin Riahy, Shadmehr Mirdar, Gholamreza Hamidian, Seyed Mohsen Afkhami, Ayoub Saeidi, Fatma Rhibi, Abderraouf Ben Abderrahman, Anthony C. Hackney and Hassane Zouhal
Adv. Respir. Med. 2019, 87(4), 226-234; https://doi.org/10.5603/ARM.2019.0037 - 30 Aug 2019
Cited by 6 | Viewed by 661
Abstract
Introduction: Evidence suggests that hypoxia and high-intensity exercise training can increase apoptosis of lung cells and Adiantum capillus-veneris (Ac-v) extract can have anti-apoptotic effects. Thus, the aim of the present study was to investigate the effect of chronic hypoxia and the (Ac-v) extraction [...] Read more.
Introduction: Evidence suggests that hypoxia and high-intensity exercise training can increase apoptosis of lung cells and Adiantum capillus-veneris (Ac-v) extract can have anti-apoptotic effects. Thus, the aim of the present study was to investigate the effect of chronic hypoxia and the (Ac-v) extraction as a supplement on TNF-a and P53 protein expression as well as the respiratory surface. Material and methods: 24 healthy Wistar rats (age = 4 weeks, weight = 72 = 9 gr) were trained using interval training for 6 weeks followed by a 3-week stay in hypoxia conditions. Half of the hypoxia samples received 500 ml/gr/per body weight daily (Ac-v) within 3 weeks of hypoxia. At the end, the lung tissue was removed for histological and immunohistological analysis. Results: After 3 weeks of hypoxia exposure following 6 weeks of exercise, expression of P53 and TNF-a increased and the respiratory surface decreased (p ≤ 0.05). After 3 weeks of taking the Ac-v extract during hypoxia exposure, reduced P53 and TNF-a expression and the increased respiratory surface were observed (p ≤ 0.05). Conclusions: Chronic hypoxia may be considered as a strong stimulus leading to the expression of proteins involved in apoptosis and tissue disruption. However, our findings suggest that the antioxidative properties of Ac-v extract could decrease the destructive structural and molecular events that happen along with hypoxia exposure or intense exercise training. Full article
172 KiB  
Letter
The Significance of Clinical Awareness of Anatomical Variations
by Ioannis Tomos, Thomas Raptakis, Nikolaos Economopoulos, Spyros A. Papiris and Anna Karakatsani
Adv. Respir. Med. 2019, 87(4), 255-256; https://doi.org/10.5603/ARM.a2019.0045 - 14 Aug 2019
Viewed by 299
Abstract
So far, diverse congenital anatomical variations have been recognized as a consequence of failed developmental process during early embryogenesis [...] Full article
3374 KiB  
Case Report
Solitary Fibrous Tumors of the Pleura: A Clinical-pathological Characterization Emphasizing Changes in Lung Function
by Heron Mendez-Sanchez, Wilbert Mendez-Vivas, Gary Kosai Vargas-Mendoza, Saul Vazquez-Lopez, Angela Dayana Williams-Jacquez and Arturo Cortes-Telles
Adv. Respir. Med. 2019, 87(4), 247-251; https://doi.org/10.5603/ARM.a2019.0042 - 14 Aug 2019
Cited by 5 | Viewed by 426
Abstract
Solitary fibrous tumors of the pleura (SFTP) represent less than 5% of all pleural tumors with a higher susceptibility for men in the sixth and seventh decades of life. Imaging and histopathological analyses indicate that these tumors have an unpredictable clinical course since [...] Read more.
Solitary fibrous tumors of the pleura (SFTP) represent less than 5% of all pleural tumors with a higher susceptibility for men in the sixth and seventh decades of life. Imaging and histopathological analyses indicate that these tumors have an unpredictable clinical course since larger tumors are often associated with malignancy; however, this assumption is not universal. In addition, there are no systematic descriptions of lung function in either the basal or post-surgical scenarios of SFTP patients. We describe a series of 3 patients between 4th and 5th decade of life with a benign histopathological SFTP without local recurrence in their follow-up. We also analyzed changes in lung function, emphasizing possible associations with clinical recovery. Full article
477 KiB  
Review
Impulse Oscillometry
by Unnati Desai and Jyotsna M. Joshi
Adv. Respir. Med. 2019, 87(4), 235-238; https://doi.org/10.5603/ARM.a2019.0039 - 14 Aug 2019
Cited by 20 | Viewed by 1763
Abstract
Pulmonary function testing involves a battery of tests from the simple pulse oximetry to the cardiopulmonary exercise testing. Impulse oscillometry (IOS) is one of the newly described pulmonary function tests. It is based on the old principle of forced oscillatory technique modified and [...] Read more.
Pulmonary function testing involves a battery of tests from the simple pulse oximetry to the cardiopulmonary exercise testing. Impulse oscillometry (IOS) is one of the newly described pulmonary function tests. It is based on the old principle of forced oscillatory technique modified and refined as per research and advances. It involves the use of sound waves during normal tidal breathing, which gives information on oscillatory pressure-flow relationships and eventually resistance and reactance. The resistance at 20 Hz (R20) represents the resistance of the large airways. The resistance at 5 Hz (R5) means the total airway resistance. (R5–R20) reflects resistance in the small airways. The reactance at 5 Hz (X5) indicates the elastic recoil of the peripheral airways. Resonant frequency and area of reactance are also measured. IOS has major uses in diagnosis and control of asthma in children and the elderly, where spirometry is otherwise normal. IOS has been studied in other respiratory diseases like COPD, ILD and supraglottic stenosis. Full article
205 KiB  
Article
Inadequate Inhaler Technique, an Everlasting Problem Associated with Poor Disease Control—A Cross-Sectional Study
by Manjulakshmi Padmanabhan, Kadhiravan Tamilarasu, Manju Rajaram and Gitanjali Batmanabane
Adv. Respir. Med. 2019, 87(4), 217-225; https://doi.org/10.5603/ARM.2019.0036 - 14 Aug 2019
Cited by 16 | Viewed by 605
Abstract
Introduction: Dry powder inhalers (DPI) have been in use in the treatment of chronic respiratory diseases for decades. DPIs require proper inhaler technique to ensure appropriate dose delivery to the lungs which in turn provides disease control and hence reduces the economic burden [...] Read more.
Introduction: Dry powder inhalers (DPI) have been in use in the treatment of chronic respiratory diseases for decades. DPIs require proper inhaler technique to ensure appropriate dose delivery to the lungs which in turn provides disease control and hence reduces the economic burden due to frequent acute attacks and hospital visits. Inadequate inhaler technique remains an everlasting problem among patients with chronic respiratory disease. Hence the aim is to assess the inhaler technique in patients using DPI and to determine the factors associated with inhaler technique. Material and methods: A cross-sectional study was conducted and 385 patients with asthma or chronic obstructive pulmonary disease (COPD) were recruited. Patient-related and disease-related factors were noted. Severity of the disease were assessed using asthma control test/COPD assessment test questionnaire and spirometer. The investigator assessed the inhaler technique of the patient against standard checklist. Results: Nearly 46.2% of the patients performed incorrect inhaler technique. Multivariate analysis showed factors like young age [Odd’s ratio (OR) 4.13, CI 1.31–17.8], well controlled disease (OR 2, CI 1.1–3.65), and the patients who learnt the technique from a medical personnel (OR 3.67, CI 1.46–9.24) had better inhaler technique. Conclusion: This study shows that the proper use of inhaler is still an unattained goal and significance of correct use has to be reiterated. Full article
195 KiB  
Article
Short Course of Systemic Corticosteroids in Wheezy Children: Still an Open Question
by Valdone Miseviciene, Gintare Liakaite and Rimantas Kevalas
Adv. Respir. Med. 2019, 87(4), 209-216; https://doi.org/10.5603/ARM.a2019.0035 - 14 Aug 2019
Cited by 2 | Viewed by 419
Abstract
Introduction: We performed a real-life clinical study to identify the main indications for the prescription of short-course treatment with systemic glucocorticosteroids (GCS) for steroid naive children with acute virus-induced wheezing as well as to analyze the influence of such treatment on patients’ serum [...] Read more.
Introduction: We performed a real-life clinical study to identify the main indications for the prescription of short-course treatment with systemic glucocorticosteroids (GCS) for steroid naive children with acute virus-induced wheezing as well as to analyze the influence of such treatment on patients’ serum cortisol level, other blood tests results and the length of stay in the hospital. Material and methods: The data of 44 patients who had acute wheezing, had no bacterial infection and were otherwise healthy were analyzed: 26 children received treatment with GCS and 18 children did not. Full blood count, biochemistry tests (Na, K, glucose) and blood cortisol levels of all patients were analyzed during treatment. Results: The main indications for the short-term administration of systemic GCS were increased work of breathing, recurrent wheezing, clinical signs of atopy and a family history of asthma. Systemic GCS increased a sodium concentration (p = 0.014), decreased a cortisol level (p = 0.038), leukocyte (p = 0.043), neutrophil (p = 0.045), and eosinophil (p < 0.001) count in blood serum. The major reduction in the eosinophil count was observed in allergic children (p = 0.023). Older age was a risk factor for cortisol suppression (p = 0.018). The average length of stay in the hospital was longer in the intervention group (p = 0.039). Conclusion: Even short-course treatment with systemic GCS decreases the serum cortisol level and has a significant effect on other blood tests results. Systemic GCS used for acute virus-induced wheezing treatment did not prove to reduce the average length of stay in the hospital. Objective criteria for initiation of such treatment are still lacking, which might consequently lead to the overuse of corticosteroids. Full article
192 KiB  
Article
Impact of Preoperative Pathological Confirmation on Surgical and Postoperative Outcomes of Lung Resection for Early Stage Lung Cancer
by Takehiro Izumo, Yuriko Terada, Minoru Inomata, Naoyuki Kuse, Nobuyasu Awano, Mari Tone, Tatsunori Jo, Hanako Yoshimura, Atsuko Moriya and Yoshiaki Furuhata
Adv. Respir. Med. 2019, 87(4), 203-208; https://doi.org/10.5603/ARM.a2019.0034 - 14 Aug 2019
Cited by 4 | Viewed by 488
Abstract
Introduction: The frequency of detection of peripheral pulmonary lesion (PPL) in suspected early lung cancer has been increasing, and whether preoperative pathological diagnosis (PPD) for small PPLs should always be established before their surgical resection can become a worrisome problem for physicians. The [...] Read more.
Introduction: The frequency of detection of peripheral pulmonary lesion (PPL) in suspected early lung cancer has been increasing, and whether preoperative pathological diagnosis (PPD) for small PPLs should always be established before their surgical resection can become a worrisome problem for physicians. The aim of the study was to clarify the impact of obtaining PPD on surgical and postoperative outcomes of lung resection for early stage lung cancer. Material and methods: This was a retrospective review of cases that underwent surgical resection for known or suspected primary lung cancer presenting pathological stage 0 or I, enrolled from June 2006 to May 2016. The patients divided into two groups according to PPD group (n = 57) and non-PPD group (n = 157) were compared. The procedure, node dissection, operation time, amount of bleeding, postoperative complications, postoperative length of stay, and postoperative recurrences were analyzed. Results: Among the 214 patients, no significant differences in operation time (248.5 ± 88.6 versus 257.6 ± 89.0, min, mean ± SD, p = 0.328), amount of bleeding (195.3 ± 176.5 vs. 188.1 ± 236.1, mL, p = 0.460), postoperative complication (5.2% vs. 4.5%, p = 0.728), postoperative length of stay (10.6 ± 6.3 vs. 10.4 ± 5.3, days, p = 0.827), or postoperative recurrences (21.0% vs. 17.2%, p = 0.550) were seen between PPD and non-PPD groups. Conclusions: Therefore, PPD had less impact on surgical and postoperative outcomes of pathological stage 0 or I lung cancer; direct surgical resection without non-surgical biopsy would be acceptable with careful selection of cases. Full article
Previous Issue
Next Issue
Back to TopTop