Advances in Respiratory Medicine

131 KiB

Open AccessLetter

Is Bronchoscopy Always Justified in Diagnosis of Haemoptysis? Response to the Letter of Tamura et al.

by Justyna Torbiarczyk, Patryk Sobczak, Katarzyna Torbiarczyk, Joanna Miłkowska-Dymanowska, Adam Antczak, Paweł Górski, Adam J. Białas and Wojciech J. Piotrowski

Adv. Respir. Med. 2018, 86(2), 111; https://doi.org/10.5603/ARM.2018.0017 - 30 Apr 2018

Cited by 1 | Viewed by 267

Abstract

Thank you very much for your interest in our recent study on the use of bronchoscopy for eval- uation of bleeding [...] Full article

123 KiB

Open AccessLetter

Bronchoscopy in Diagnosis of Haemoptysis

by Tomohiro Tamura, Toshihiro Shiozawa, Kunihiko Miyazaki and Hiroaki Satoh

Adv. Respir. Med. 2018, 86(2), 110; https://doi.org/10.5603/ARM.2018.0016 - 30 Apr 2018

Viewed by 279

Abstract

With great interest, we read the article by Torbiarczyk et al. on bronchoscopy in diagnosis of haemoptysis (Adv Respir Med. 2018; 86: 13–16) [...] Full article

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Open AccessReview

Can Vitamin D Help in Achieving Asthma Control? Vitamin D “Revisited”: An Updated Insight

by Izabela Szymczak and Rafał Pawliczak

Adv. Respir. Med. 2018, 86(2), 103-109; https://doi.org/10.5603/ARM.2018.0015 - 30 Apr 2018

Cited by 5 | Viewed by 336

Abstract

Asthma—a prolonged respiratory disease related with hyper-responsiveness and increased inflammation of airways; affects millions peoples worldwide. Vitamin D possess anti-inflammatory and immunomodulatory activities. Its deficiency (the level less than 20 ng/mL in the serum) is found to be related to occurrence of pulmonary [...] Read more.

Asthma—a prolonged respiratory disease related with hyper-responsiveness and increased inflammation of airways; affects millions peoples worldwide. Vitamin D possess anti-inflammatory and immunomodulatory activities. Its deficiency (the level less than 20 ng/mL in the serum) is found to be related to occurrence of pulmonary diseases including bacterial and viral infections and asthma. Some studies indicate that low levels of vitamin D in the serum are related to reduced lung function and increased airway inflammation as well as overall poor results in asthmatic patients. Thus, it provides positive relation between vitamin D and asthma. Increased prevalence of asthma over the past decades causes elevated interest in vitamin D supplementation that is even reported as a “potential therapeutic option”. Unfortunately, results of clinical trials are inconsistent and do not provide supportive information about positive role of vitamin D in asthma. Little or even no effect of supplementation of vitamin D in improvement of onset, symptoms or progression of asthma was found in comprehensive interventional studies in adults, children and pregnant woman. This review critically summarized the last years evidence of a relation between vitamin D and asthma in adults, children and pregnant women. Full article

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Open AccessCase Report

Thoracic Ultrasound for the Detection of Rib Metastases of Non-Small Cell Lung Cancer

by Ioannis Tomos, Nikos Tziolos, Thomas Raptakis and Dimitra Kavatha

Adv. Respir. Med. 2018, 86(2), 101-102; https://doi.org/10.5603/ARM.2018.0014 - 30 Apr 2018

Cited by 3 | Viewed by 352

Abstract

Transthoracic ultrasound has lately emerged as a useful diagnostic tool for respiratory physicians in the diagnosis of diverse pulmonary diseases, usually including pleural effusion and pneumothorax. However, the use of chest ultrasound may be also critical in the evaluation of chest wall diseases. [...] Read more.

Transthoracic ultrasound has lately emerged as a useful diagnostic tool for respiratory physicians in the diagnosis of diverse pulmonary diseases, usually including pleural effusion and pneumothorax. However, the use of chest ultrasound may be also critical in the evaluation of chest wall diseases. Therefore, we present an interesting case of a patient with metastases of lung cancer to the rib, detected during the chest wall ultrasound examination. By representing a non-invasive, surface-imaging technique with several advantages, chest ultrasound may evolve to a valid, bed-side diagnostic tool for the diagnosis and follow up of lung cancer with metastases in the chest wall. Full article

532 KiB

Open AccessCase Report

Acrometastasis due to Lung Adenocarcinoma

by Vasiliki Apollonatou, Stelios Loukides, Andriana I. Papaioannou and Spyros Papiris

Adv. Respir. Med. 2018, 86(2), 97-100; https://doi.org/10.5603/ARM.2018.0013 - 30 Apr 2018

Cited by 5 | Viewed by 358

Abstract

We are presenting a case of acrometastasis in a male patient with lung adenocarcinoma. Acrometastases accumulate for 0.1% of all metastatic bone lesions and can be the first manifestation of cancer in approximately 10% of cases. The main clinical manifestations are tenderness, intermittent [...] Read more.

We are presenting a case of acrometastasis in a male patient with lung adenocarcinoma. Acrometastases accumulate for 0.1% of all metastatic bone lesions and can be the first manifestation of cancer in approximately 10% of cases. The main clinical manifestations are tenderness, intermittent pain, functional impairment, erythema, heat and swelling of the affected part. Lung cancer is the main primary malignancy which causes acrometastases. Although the lesions can be recognized in X-rays or CT scans, the gold standard for the diagnosis is MRI scan in which the full extension of the tumor can be evaluated. The diagnosis is usually confirmed by fine-needle biopsy of the affected bone. In the presence of acrometastases, prognosis is very poor and palliative treatment is usually recommended. This case shows that patients at risk for lung cancer should be screened intensively when they develop persistent digital symptoms. Full article

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Open AccessCase Report

Pulmonary Tuberculosis Mimicking Lung Cancer Progression after 10 Years of Cancer Remission

by Justyna Fijołek, Elzbieta Wiatr, Malgorzata Polubiec-Kownacka, Katarzyna Blasińska-Przerwa, Malgorzata Szolkowska, Ewa Szczepulska-Wojcik and Kazimierz Roszkowski-Sliz

Adv. Respir. Med. 2018, 86(2), 92-96; https://doi.org/10.5603/ARM.2018.0012 - 30 Apr 2018

Cited by 5 | Viewed by 445

Abstract

Differentiation between pulmonary tuberculosis and lung cancer is often challenging for clinicians, especially that both conditions can coexist. This is due to the fact that the clinical and radiological symptoms of both diseases can be similar. Our Case Report presents a patient who [...] Read more.

Differentiation between pulmonary tuberculosis and lung cancer is often challenging for clinicians, especially that both conditions can coexist. This is due to the fact that the clinical and radiological symptoms of both diseases can be similar. Our Case Report presents a patient who was treated for advanced lung cancer 10 years earlier and currently has been hospitalized again because of a strong clinical and radiological suspicion of the cancer progression, but whose final diagnosis was tuberculosis. Full article

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Open AccessArticle

Coping with Stress by Mothers of Children and Adolescents with Cystic Fibrosis

by Renata Zubrzycka

Adv. Respir. Med. 2018, 86(2), 86-91; https://doi.org/10.5603/ARM.2018.0011 - 30 Apr 2018

Cited by 4 | Viewed by 471

Abstract

Introduction: Studies of coping with stress of parents of children with cystic fibrosis (CF) are relatively rare and their results are inconsistent. The aim of the work was to determine the strategies of coping with stress of Polish mothers of children and [...] Read more.

Introduction: Studies of coping with stress of parents of children with cystic fibrosis (CF) are relatively rare and their results are inconsistent. The aim of the work was to determine the strategies of coping with stress of Polish mothers of children and adolescents with CF. Material and methods: The research was conducted in the group of 89 Polish mothers of children with CF (0–18) and used the Brief COPE by Carver in the Polish adaptation by Juczyński and Ogińska-Bulik (2009). The data were compared with the normative results obtained from Polish adults. Results: The strategies of coping most often used by mothers of children with CF are as follows: active coping, planning and acceptance. A comparison of mean results obtained in the research group and mean results of adults in Polish population revealed that mothers of ill children significantly more often use: active coping, planning, positive reframing, acceptance, religion, seeking of instrumental support and venting. They less often use sense of humour and take psychoactive substance. Use of problem--oriented strategies dominated over use of coping strategies focusing on emotions. Conclusion: Social support provided to mothers of children with CF should be oriented on strengthening cognitive strategies of coping with stress. Full article

456 KiB

Open AccessArticle

Vitamin D Status of Severe COPD Patients with Chronic Respiratory Failure

by Grzegorz Gawron, Marzena Trzaska-Sobczak, Ewa Sozańska, Piotr Śnieżek and Adam Barczyk

Adv. Respir. Med. 2018, 86(2), 78-85; https://doi.org/10.5603/ARM.2018.0010 - 30 Apr 2018

Cited by 3 | Viewed by 400

Abstract

Introduction: The aim of the study was to measure the concentrations of vitamin D in serum of COPD patients with chronic respiratory failure in comparison to healthy control group. The correlation between the levels of vitamin D in serum and the selected [...] Read more.

Introduction: The aim of the study was to measure the concentrations of vitamin D in serum of COPD patients with chronic respiratory failure in comparison to healthy control group. The correlation between the levels of vitamin D in serum and the selected clinical, spirometric and blood gas parameters was the additional aim of the study. Material and methods: The study included 61 patients with diagnosed COPD in stadium of chronic respiratory failure (45 men and 16 women) and 37 healthy controls (19 men and 18 women). The following procedure were performed in all studied subjects: detailed history (especially: daily activity, diet, tobacco and alcohol use), post-bronchodilator spirometry, assessment of 25(OH)D in serum and for COPD group only blood gas analysis. Recruitment for the study was conducted from November to April. Statistical analysis was performed using the following statistical methods: t-Student test, Mann-Whitney U test, Spearman correlation test and Chi-kwadrat test. Results: There was no significant differences between COPD and control group for the levels of 25(OH)D in serum. Median and lower; upper quartile were respectively following: 24.75 nmol/l (16.9; 36.4) vs. 24.06 nmol/l (16.3; 37.2), p = 0.69. Vitamin D deficiency was present in 60 COPD patients (98.3% of all patients) and in 36 control group subject (97.3% of all healthy volunteers). The difference was not statistically significant. The levels of vitamin D in serum did not significantly correlated with any of studied parameters (spirometry, blood gas, age, the level of activity, BMI, tobacco smoke exposure and others). However, the level of activity in COPD group correlated positively with spirometry values and negatively with age and number of exacerbations. Conclusion: The results of the study showed that in autumn-winter time in Poland there are very frequent deficiency of vitamin D in serum not only in COPD patients in respiratory failure stage but also in elderly healthy persons. However, in contrary to expectations the deficiency of vitamin D in COPD patients with respiratory failure were similar to that seen in healthy persons. Full article

160 KiB

Open AccessArticle

Prevalence and Predictors of Readmissions among Adults with Cystic Fibrosis in the United States

by Kshitij Chatterjee, Abhinav Goyal, Deepak Reddy, Vikas Koppurapu, Ayoub Innabi, Bashar Alzghoul and Rajani Jagana

Adv. Respir. Med. 2018, 86(2), 75-77; https://doi.org/10.5603/ARM.2018.0006 - 30 Apr 2018

Viewed by 340

Abstract

Introduction: Patients with Cystic Fibrosis (CF) have increasing rates of hospitalization. We analyzed the burden and predictors of thirty-day readmission among patients with CF in the U.S. Material and methods: Nationwide Readmission Database (NRD) 2013 was used to identify adults with [...] Read more.

Introduction: Patients with Cystic Fibrosis (CF) have increasing rates of hospitalization. We analyzed the burden and predictors of thirty-day readmission among patients with CF in the U.S. Material and methods: Nationwide Readmission Database (NRD) 2013 was used to identify adults with CF who were hospitalized. These individuals were followed to determine the prevalence of readmission within thirty days of index discharge. Cox proportional hazard regression was used to identify independent predictors of readmission. Results: There were 14,616 index admissions of adults with CF in 2013. Of these, 2606 (17.8%) patients were readmitted within 30 days of discharge. Female sex and chronic anemia were independent predictors of readmission. The most common causes of readmission were pulmonary exacerbation (31%), lung transplant complications (5.2%), and septicemia (3.4%). Conclusion: Readmissions are frequent among adults with CF and contribute to significant healthcare burden and cost among this population. Full article

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Adv. Respir. Med., Volume 86, Issue 2 (April 2018) – 9 articles , Pages 75-111

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