Advances in Respiratory Medicine

476 KiB

Open AccessCase Report

Unilateral Hypertransparency on Chest Radiograph: The Congenital Poland Syndrome

by Ioannis Tomos, Andriana I. Papaioannou, Aikaterini Vlami, Vasiliki Apollonatou, Effrosyni D. Manali and Spyros A. Papiris

Adv. Respir. Med. 2016, 84(6), 342-343; https://doi.org/10.5603/ARM.2016.0045 - 07 Dec 2016

Cited by 2 | Viewed by 319

Abstract

Unilateral hypertransparent hemithorax requires a particular diagnostic approach as it can be the result of diverse pulmonary diseases, including pneumothorax, large pulmonary embolus, unilateral large bullae, mucous plag, airway obstruction and contralateral pleural effusion. Congenital syndromes with chest wall abnormalities, are rare, but [...] Read more.

Unilateral hypertransparent hemithorax requires a particular diagnostic approach as it can be the result of diverse pulmonary diseases, including pneumothorax, large pulmonary embolus, unilateral large bullae, mucous plag, airway obstruction and contralateral pleural effusion. Congenital syndromes with chest wall abnormalities, are rare, but often underdiagnosed causes. Poland Syndrome consists of such a rare, congenital anomaly and is characterized by the absence of the pectoralis major muscle and upper limb ipsilateral abnormalities. We present a case of a patient with acute exacerbation of chronic obstructive pulmonary disease (COPD) and a unilateral hypertransparency on chest radiology, attributed to the underlying Poland Syndrome. Full article

651 KiB

Open AccessCase Report

Fire-Eater’s Lung

by Jolanta Załęska, Arkadiusz Błaszczyk, Lilia Jakubowska, Janusz Szopiński, Mateusz Polaczek, Jacek Grudny, Jacek Zych and Kazimierz Roszkowski-Śliż

Adv. Respir. Med. 2016, 84(6), 337-341; https://doi.org/10.5603/ARM.2016.0044 - 07 Dec 2016

Cited by 2 | Viewed by 542

Abstract

Fire eater’s lung (FEL) is an acute hydrocarbon pneumonitis caused by aspiration or inhalation into airways of liquid hydrocarbons. This disorder is classified into distinct form of chemical toxic pneumonitis. An amateur fire-eater is presented in this work. He accidentally aspirated into airways [...] Read more.

Fire eater’s lung (FEL) is an acute hydrocarbon pneumonitis caused by aspiration or inhalation into airways of liquid hydrocarbons. This disorder is classified into distinct form of chemical toxic pneumonitis. An amateur fire-eater is presented in this work. He accidentally aspirated into airways about 1/3 of glass of grill lighter fluid composed of mixture of liquid hydrocarbons. A few hours after this incident he had severe symptoms like weakness, high temperature, midsternal pleuritic chest pain, myalgia of the back, shortness of breath, and dry cough. Radiologic examination revealed consolidations with well−defined cavitary lesions (pneumatoceles) in lower lobes mainly in the left lower lobe. After one week of this event clinical improvement was observed. The lesions resolved nearly completly during three months. The review of the literature connected with fire-eater’s lung is also presented. Full article

148 KiB

Open AccessReview

Pain Management in Lung Cancer

by Fariz Nurwidya, Elisna Syahruddin and Faisal Yunus

Adv. Respir. Med. 2016, 84(6), 331-336; https://doi.org/10.5603/ARM.2016.0043 - 07 Dec 2016

Cited by 4 | Viewed by 432

Abstract

Lung cancer is the leading cause of cancer-related mortality worldwide. Not only burdened by the limited overall survival, lung cancer patient also suffer from various symptoms, such as pain, that implicated in the quality of life. Cancer pain is a complicated and transiently [...] Read more.

Lung cancer is the leading cause of cancer-related mortality worldwide. Not only burdened by the limited overall survival, lung cancer patient also suffer from various symptoms, such as pain, that implicated in the quality of life. Cancer pain is a complicated and transiently dynamic symptom that results from multiple mechanisms. This review will describe the pathophysiology of cancer pain and general approach in managing a patient with lung cancer pain. The use of opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and adjuvant analgesia, as part of the pharmacology therapy along with interventional strategy, will also be discussed. Full article

571 KiB

Open AccessArticle

A Clinic-Epidemiological Study of Head and Neck Tuberculosis—A Single-Center Experience

by Anna Maria Pajor, Magdalena Józefowicz-Korczyńska, Maria Korzeniewska-Koseła and Sylwia Kwiatkowska

Adv. Respir. Med. 2016, 84(6), 324-330; https://doi.org/10.5603/ARM.2016.0042 - 07 Dec 2016

Cited by 8 | Viewed by 381

Abstract

Introduction: Extrapulmonary tuberculosis (EPTB) accounts for less than 6% of all tuberculosis (TB) cases in Poland, although in other countries (European in particular) this proportion is much higher. The study was undertaken to evaluate the clinical and epidemiological differences in patients hospitalized in [...] Read more.

Introduction: Extrapulmonary tuberculosis (EPTB) accounts for less than 6% of all tuberculosis (TB) cases in Poland, although in other countries (European in particular) this proportion is much higher. The study was undertaken to evaluate the clinical and epidemiological differences in patients hospitalized in one of Otolaryngology Departments in Poland during 36 years. Material and methods: In a retrospective study, 71 patients were identified and divided into three groups according to the study period: I—1978−1989 (30 patients, 42%), II—1990−2001 (19 patients, 27%) and III—2002−2013 (22 patients, 31% of all cases). In each case histological examination of biopsy specimens was available. Results: Larynx TB (54.9%) was most common, followed by cervical lymph nodes TB (29.6%) and auris TB (8.5%). In laryngeal TB, glottic region was most often affected (76.9%). Patients with larynx TB were mainly men (87.2%), 10 years older than women in each study period. However, in lymph nodes TB group, women constituted 66.7% of cases and were twice as old as men (64.0 vs. 34.7 yrs). Bacteriological confirmation was made in only one patient. Conclusions: The number of patients diagnosed in our center declined in the first period of 12 years and remained stable over the last 24 years, as were the common sites of head and neck EPTB (larynx and cervical lymph nodes). In patients with head and neck TB the biopsy specimens should be examined not only histologically but also for the presence of Mycobacterium tuberculosis. Full article

178 KiB

Open AccessArticle

Contemporary National Trends of Cystic Fibrosis Hospitalizations and Co-Morbidities in the United States

by Kshitij Chatterjee, Abhinav Goyal, Nishi Shah, Krishna Kakkera, Rajani Jagana and Paula Anderson

Adv. Respir. Med. 2016, 84(6), 316-323; https://doi.org/10.5603/ARM.2016.0041 - 07 Dec 2016

Cited by 8 | Viewed by 441

Abstract

Introduction: Cystic fibrosis (CF) is a life-limiting multisystemic genetic disease. Patients with CF have a high rate of hospitalization. We attempt to ascertain national trends of inpatient stays, prevalence of various co-morbidities during hospitalizations, outcomes and discharge disposition among CF patients. Material and [...] Read more.

Introduction: Cystic fibrosis (CF) is a life-limiting multisystemic genetic disease. Patients with CF have a high rate of hospitalization. We attempt to ascertain national trends of inpatient stays, prevalence of various co-morbidities during hospitalizations, outcomes and discharge disposition among CF patients. Material and methods: Data from the National Inpatient Sample (NIS) was used to identify all hospitalizations of patients with CF and their demographic characteristics from 2003 to 2013. Prevalence and effects of various co-morbidities like acute kidney injury (AKI) were determined. Detailed sub-group analysis was performed for individuals with lung transplant. Results: The annual rate of hospitalization per 1000 CF patients in the U.S. increased from 994 in 2003 to 1072 in 2013. The overall in-hospital mortality was 1.5%; median age at death was 27 years. In-hospital mortality trended down from 1.9% to 1.2% from 2003 to 2013 (p-value for trend: 0.002). The median length of stay was 7 days. The prevalence of chronic liver disease and AKI was 3.7% and 3.8% respectively. Multivariate adjusted odds of mortality for AKI was 1.74 (95% CI 1.57−1.93, p < 0.001). Patients with prior lung transplantation accounted for 6.5% of hospitalizations. These patients had a significantly higher prevalence of AKI. Conclusions: The annual hospitalization rates of CF patients is increasing over the years. Females with CF constitute a higher proportion of hospitalized patients despite a higher male preponderance of males with CF in the community. AKI is associated with a significantly higher in-hospital mortality. Lung transplant recipients have a higher prevalence of AKI and mortality. Full article

182 KiB

Open AccessArticle

Long Term Outcome of Cystic Fibrosis Patients with Multisystem Evaluation

by Maryam Hassanzad, Mohammad Reza Boloursaz, Sepideh Darougar, Sabereh Tashayoie Nejad, Seyed Amir Mohajerani, Nooshin Baghaie, Seyed Karen Hashemitari and Ali Akbar Velayati

Adv. Respir. Med. 2016, 84(6), 310-315; https://doi.org/10.5603/ARM.2016.0040 - 07 Dec 2016

Cited by 7 | Viewed by 500

Abstract

Introduction: Cystic fibrosis is a chronic disease with multiple organ involvement and chiefly results in chronic respiratory infections, pancreatic insufficiency and associated complications. The age at diagnosis, clinical presentation, rate of disease progression and prognosis is variable among patients. This study is designed [...] Read more.

Introduction: Cystic fibrosis is a chronic disease with multiple organ involvement and chiefly results in chronic respiratory infections, pancreatic insufficiency and associated complications. The age at diagnosis, clinical presentation, rate of disease progression and prognosis is variable among patients. This study is designed to evaluate the behavior of disease to provide epidemiologic data for early recognition and proper management. Material and methods: The study was designed as an active surveillance of 192 patients diagnosed with cystic fibrosis in a tertiary lung disease centre between 2008 and 2015. The diagnosis of cystic fibrosis was established in all patients accordingly to conventional criteria, including two positive sweat chloride tests and clinical signs and symptoms. Demographic, clinical and laboratory data were obtained from these patients in each hospitalization and also every follow-up visit and carefully evaluated for complications of this chronic disease. Results: The majority of patients showed positive culture for Pseudomonas aeroginosa. Bronchiectasis was the most prevalent finding in chest CT scan. 44.3% of patients had been treated for allergic bronchopulmonary aspergillosis and all had sinus disease. Increased pulmonary artery pressure was observed in 40% of patients with cystic fibrosis. 33 patients died which consisted 17.1% of all the patients.The mean age of mortaliy was 18.15 year. Conclusions: The clinical outcome of cystic fibrosis is variable in different countries which may reflect environmental influences and the role of early diagnosis on long term outcomes. However, the role of early diagnosis in long-term outcomes of the disease can not be ignored. Full article

108 KiB

Open AccessEditorial

Living Better and Longer with Cystic Fibrosis

by Szczepan Cofta

Adv. Respir. Med. 2016, 84(6), 307-309; https://doi.org/10.5603/ARM.2016.0039 - 07 Dec 2016

Viewed by 285

Abstract

Cystic fibrosis (CF) is the most common autosomal recessive disorder in Caucasians [...] Full article

109 KiB

Open AccessEditorial

Change of the Title: “Pneumonologia i Alergologia Polska” Becomes “Advances in Respiratory Medicine”

by Wojciech Piotrowski

Adv. Respir. Med. 2016, 84(6), 1; https://doi.org/10.5603/ARM.54105 - 07 Dec 2016

Cited by 1 | Viewed by 328

Abstract

Since 2015 we have introduced several changes to our Journal [...] Full article

Journal Menu

Journal Browser

Adv. Respir. Med., Volume 84, Issue 6 (December 2016) – 8 articles , Pages 1-343

Further Information

Guidelines

MDPI Initiatives

Follow MDPI