Next Article in Journal
The Accessibility and Understanding of Nutrition Advice in First Time Mothers
Previous Article in Journal
Dietary Intake of New Zealand Strength Athletes
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Abstract

Do Lactose Intolerant Individuals Efficiently Absorb Protein from Acute Milk Consumption? †

1
Liggins Institute, The University of Auckland, Auckland 1023, New Zealand
2
The Riddet Institute, Palmerston North 4442, New Zealand
3
Department of Food Technology and Nutritional Science, Mawlana Bhashani Science and Technology University, Tangail 1902, Bangladesh
4
Faculty of Medicine and Health Science, Linköping University, Linköping 581 83, Sweden
5
Food Nutrition & Health Team, AgResearch Limited, Palmerston North 4442, New Zealand
6
The High-Value Nutrition National Science Challenge, Auckland 1023, New Zealand
7
Food & Bio-based Products Group, AgResearch Limited, Palmerston North 4442, New Zealand
*
Author to whom correspondence should be addressed.
Presented at the 2018 Nutrition Society of New Zealand Annual Conference, Auckland, New Zealand, 28–30 November 2018.
Proceedings 2019, 8(1), 39; https://doi.org/10.3390/proceedings2019008039
Published: 12 March 2019
(This article belongs to the Proceedings of 2018 Annual Meeting of the Nutrition Society of New Zealand)
Background: Lactose intolerance is due to the malabsorption of lactose, the predominant sugar present in milk. Although this has known impacts on lower gastrointestinal digestive processes (including diarrhoea), the impact on total gastrointestinal transit along with the digestion and absorption of other nutrients has not been investigated. Hence this study was undertaken to understand whether lactose intolerance impacts postprandial amino acid (AA) concentrations following milk ingestion.
Methods: Twenty young women enrolled in this double-blind, randomised crossover trial were classified as either lactose intolerant (LI, n = 10) or dairy tolerant (DT, n = 10) after a standardised lactose challenge (50 g), based on markers of malabsorption and symptoms. Each group was then provided with 750 mL of UHT-treated conventional milk, a2 MilkTM and lactose-free milk. Fasting and postprandial plasma samples were collected and analysed for AA concentrations using ultra-performance liquid chromatography.
Results: Relative to dairy tolerant group, lactose intolerant group had higher plasma concentrations of glutamic acid in response to all the milk types (p < 0.05 each, respectively). However, in response to a2 MilkTM, dairy tolerant group had higher circulatory concentrations of threonine compared to lactose intolerant group (p < 0.05). Compared to conventional milk, both groups had higher plasma concentrations of threonine, alanine, proline and glutamic acid in response to lactose-free milk (p < 0.05 each, respectively). However, in response to lactose-free milk, both groups had higher plasma concentrations of alanine and proline compared to a2 MilkTM (p < 0.05 each, respectively). Additionally, in lactose intolerant group, threonine was found higher with lactose-free milk than a2 MilkTM, glutamic acid was higher with conventional milk than lactose-free milk and alanine was higher with conventional milk than a2 MilkTM (p < 0.05 each, respectively).
Conclusions: Lactose intolerance has little impact on postprandial plasma levels of specific AAs. This response did not differ between conventional or a2 MilkTM, however lactose-free milk altered protein digestibility.

Supplementary Material

The oral presentation is available online at www.mdpi.com/2504-3900/8/1/39/s1.

Share and Cite

MDPI and ACS Style

Prodhan, U.K.; Shrestha, A.; Karlström, H.J.; Martinsson, J.A.; Nilsson, N.J.; Barnett, M.P.G.; Milan, A.M.; Cameron-Smith, D. Do Lactose Intolerant Individuals Efficiently Absorb Protein from Acute Milk Consumption? Proceedings 2019, 8, 39. https://doi.org/10.3390/proceedings2019008039

AMA Style

Prodhan UK, Shrestha A, Karlström HJ, Martinsson JA, Nilsson NJ, Barnett MPG, Milan AM, Cameron-Smith D. Do Lactose Intolerant Individuals Efficiently Absorb Protein from Acute Milk Consumption? Proceedings. 2019; 8(1):39. https://doi.org/10.3390/proceedings2019008039

Chicago/Turabian Style

Prodhan, Utpal Kumar, Aahana Shrestha, Helga Josefin Karlström, Jakob Andre Martinsson, Nils Jimmy Nilsson, Mathew Philip Greig Barnett, Amber Marie Milan, and David Cameron-Smith. 2019. "Do Lactose Intolerant Individuals Efficiently Absorb Protein from Acute Milk Consumption?" Proceedings 8, no. 1: 39. https://doi.org/10.3390/proceedings2019008039

Article Metrics

Back to TopTop