Structural Integrity and Functional Neural Activity Associated with Oral Language Function after Stroke
Abstract
:1. Introduction
2. Materials and Methods
2.1. Patients
2.2. Language Evaluation
2.3. MRI Preprocessing
2.4. Statistical Analysis
3. Results
3.1. Patient Characteristics
3.2. Structural Atrophy Associated with Language Function
3.3. Functional Neural Activity Associated with Language Function
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameter | T1-Weighed MRI | DTI | rsfMRI |
---|---|---|---|
Matrix | 256 × 256 | 112 × 112 | 64 × 64 |
Field of view (mm2) | 230 × 230 | 224 × 224 | 192 × 192 |
Repetition time (ms) | 1900 | 9700 | 2000 |
Echo time (ms) | 2.57 | 92.00 | 30.00 |
Slice thickness (mm) | 1 | 2 | 4.4 |
Flip angle (°) | 9 | 9 | 9 |
Directions | 30 | ||
b values (s/mm2) | 1000 |
(n = 20)/Mean ± SE/n (%) | |
---|---|
Demographic characteristics | |
Age (years) | 71.9 ± 2.4 |
Duration between stroke and performed MRI (days) | 1219.7 ± 432.6 |
Language evaluation (K-WAB) | |
Spontaneous speech (20) | 11.1 ± 1.7 |
Comprehension (10) | 6.5 ± 0.7 |
Repetition (10) | 6.0 ± 1.0 |
Naming (10) | 5.5 ± 0.9 |
Aphasia severity | |
Mild | 6 (30.0%) |
Mild to moderate | 6 (30.0%) |
Moderate | 1 (5.0%) |
Moderate to severe | 0 (0%) |
Severe | 7 (35.0%) |
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Kyeong, S.; Kang, H.; Kim, D.H. Structural Integrity and Functional Neural Activity Associated with Oral Language Function after Stroke. J. Clin. Med. 2022, 11, 3028. https://doi.org/10.3390/jcm11113028
Kyeong S, Kang H, Kim DH. Structural Integrity and Functional Neural Activity Associated with Oral Language Function after Stroke. Journal of Clinical Medicine. 2022; 11(11):3028. https://doi.org/10.3390/jcm11113028
Chicago/Turabian StyleKyeong, Sunghyon, Hyunkoo Kang, and Dae Hyun Kim. 2022. "Structural Integrity and Functional Neural Activity Associated with Oral Language Function after Stroke" Journal of Clinical Medicine 11, no. 11: 3028. https://doi.org/10.3390/jcm11113028