Next Issue
Volume 12, December
Previous Issue
Volume 12, May
 
 
Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Hematol. Rep., Volume 12, Issue 2 (November 2020) – 5 articles

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
  • You may sign up for e-mail alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Order results
Result details
Select all
Export citation of selected articles as:
2 pages, 306 KiB  
Case Report
Six Cases of Autoimmune Acquired Coagulation Factor VIII Deficiency: Single Center Experience in Japan
by Akiko Konishi, Aya Nakaya, Kazuyoshi Ishii and Shosaku Nomura
Hematol. Rep. 2020, 12(2), 8525; https://doi.org/10.4081/hr.2020.8525 - 2 Dec 2020
Viewed by 435
Abstract
We report six cases of autoimmune acquired coagulation factor VIII deficiency, which is a rare bleeding disorder. It is an autoimmune disease, however, there are various causes. We experienced cases with malignancy, co-exist with another autoimmune disease, pregnancy, and unknown epidemiology with repeated [...] Read more.
We report six cases of autoimmune acquired coagulation factor VIII deficiency, which is a rare bleeding disorder. It is an autoimmune disease, however, there are various causes. We experienced cases with malignancy, co-exist with another autoimmune disease, pregnancy, and unknown epidemiology with repeated bleeding episode. All patients were controlled the acute bleeding phase and they have been under treatment with immunosuppression. Full article
4 pages, 359 KiB  
Article
Haematological Abnormalities and Risk of COVID-19 Infection in Adult Patients Attending Primary Fealthcare Settings
by Ehab Hamed, Mohamed Ahmed Syed, Ahmed Sameer Alnuaimi, Mohammed Soliman, Bayan Alemrayat, Amina Ali Mohamed Muktar, AlAnoud Saleh AlFehaidi and Hamda Abdulla AlQotba
Hematol. Rep. 2020, 12(2), 8829; https://doi.org/10.4081/hr.2020.8829 - 17 Nov 2020
Cited by 2 | Viewed by 662
Abstract
Centres for Disease Control and prevention (CDC) reports that there are limited data and information about the impact of underlying medical conditions and the risk of infection. To date, there are no studies that report on the risk of infection among patients with [...] Read more.
Centres for Disease Control and prevention (CDC) reports that there are limited data and information about the impact of underlying medical conditions and the risk of infection. To date, there are no studies that report on the risk of infection among patients with haematological diseases or abnormalities. This cross-sectional study reports on the baseline complete blood count in patients attending publicly funded primary care settings with a diagnosis of suspected COVID-19 infections in the state of Qatar. The study will report on the descriptive characteristics of the population, including gender, age and prior abnormalities to their blood test results. We will compare the results of those with positive and negative PCR test results, where appropriate. Nine hundred sixty-two adult patients attended publicly funded primary health care settings in the state of Qatar between 10 February and 30 April 2020 with a diagnosis of suspected COVID-19 infections had prior recorded blood investigations in the last six months and were included in this study. The population was young, mean of age is 38.8 ± 11.6. (Median: 36 [Min: 19–Max: 85]). Complete blood count of the sample had minimal missing data points. Females were more presented in our samples, Female (n = 560, 58.21%) and Male (n = 402, 41.79%). Most of our sample had a documented PCR test result, negative (n = 831, 86.38%); positive (n = 123, 12.79%) and missing (n = 8, 0.83%). Low haemoglobin values (n = 265, 27.5%) and low red blood cell count (n = 170, 17.7%) were the most prevalent complete blood count abnormality in the population. Leukopenia was less common (n = 50, 8.2%). Most of the population had normal platelet count (n = 895, 93%). Gender was the most influential factor in our sample to increase the odds of having a positive PCR t results; males were more likely to be affected (p < 0.001, Chi-square test) (OR 2.56, 95% CI 1.73–3.77). Categories for haematological abnormalities were not associated with increased risk of having a positive PCT test result. In a population attending primary healthcare settings with early presentation of symptoms of COVID-19 infection, the risk of infection among our cohort was not affected by the prior haematological values of those patients. Gender was the most influential parameter in the risk of infection in our population. Analysis of the results using gender-specific categories for different haematological parameters suggested that patients with abnormal haematological values were not at increased risk of having a positive COVID-19 infection. Full article
4 pages, 371 KiB  
Article
Surgery Results in Low Relapse and Progression Rates in Extramedullary Plasmacytoma of the Head and Neck: A Case Cohort and Review of the Literature
by Matevz Skerget, Tadej Dovsak, Gregor Kos and Samo Zver
Hematol. Rep. 2020, 12(2), 8396; https://doi.org/10.4081/hr.2020.8396 - 17 Nov 2020
Cited by 3 | Viewed by 452
Abstract
Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10–30%. In our case-cohort, thorough, sensitive initial [...] Read more.
Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10–30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression. Full article
5 pages, 419 KiB  
Article
Impact of Activated Monocyte and Endothelial Dysfunction on Coagulopathy in Egyptian Adult Beta Thalassemic Patients
by Hanaa Abd El-samee, Noha Bassiouny and Nermeen Adel Nabih
Hematol. Rep. 2020, 12(2), 8365; https://doi.org/10.4081/hr.2020.8365 - 17 Nov 2020
Cited by 2 | Viewed by 488
Abstract
The mechanism of the well observed hypercoagulability and high incidence of Thromboembolic Events (TE) in β-thalassemia patients has not been fully elucidated. This study aimed to evaluate evaluate the endothelial dysfunction and monocyte activation among adult Egyptian β-thalassemic patients and assess their role [...] Read more.
The mechanism of the well observed hypercoagulability and high incidence of Thromboembolic Events (TE) in β-thalassemia patients has not been fully elucidated. This study aimed to evaluate evaluate the endothelial dysfunction and monocyte activation among adult Egyptian β-thalassemic patients and assess their role in the hypercoagulability and development of TE. A total of 40 adults patients with bthalassemics and 20 healthy age and sex-matched controls were assessed for endothelial dysfunction using serum Von Willebrand Factor Antigen (VWFAg) and for monocytic activation using flow cytometric assessment of CD14 monocyte microparticles and CD11b activated monocytes. The VWF:Ag level was significantly higher among thalassemic patients (p < 0.001) and was positively correlated to development of TE (p < 0.05). There was no significance difference for CD14 between patients and controls (p > 0.5) and CD11b was higher in controls (p = 0.004) with no significant correlation between both and TE development (p > 0.05). VWF:Ag is increased in thalassemic patients and could be used as a risk factor for thrombosis in these patients, while no identified role of activated monocytes in thrombotic tendency in such patients. Full article
1 pages, 254 KiB  
Erratum
ERRATUM: A Unique Case of Durable Complete Remission after Salvage with Azacitidine and DLI for High Risk Flt-3 Positive Acute Myeloid Leukemia, Following Relapse 18 Months Post Allogeneic Stem Cell Transplant
by Claire Horgan, Alexandros Kanellopoulos, Shankara Paneesha, Bhuvan Kishore, Richard Lovell and Emmanouil Nikolousis
Hematol. Rep. 2020, 12(2), 8995; https://doi.org/10.4081/hr.2020.8995 - 16 Nov 2020
Viewed by 411
Abstract
Due to an error, Dr. Nikolousis’s last name was mistakenly spelled in this article (published in 2019 in Hematology Reports DOI: 10.4081/hr.2019.7800) [...] Full article
Previous Issue
Next Issue
Back to TopTop