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Article

Splenomegaly Impacts Prognosis in Essential Thrombocythemia and Polycythemia Vera: A Single Center Study

1
Hematology Division, University Hospital Policlinico “Paolo Giaccone”, Via del Vespro 129, 90127 Palermo, Italy
2
Department of Surgical, Oncological and StomatologicalDisciplines, University of Palermo, 90133 Palermo, Italy
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2019, 11(4), 8281; https://doi.org/10.4081/hr.2019.8281
Submission received: 20 August 2019 / Revised: 20 October 2019 / Accepted: 18 November 2019 / Published: 4 December 2019

Abstract

Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact that such alteration has on thrombotic risk and on the survival of patients with essential thrombocythemia and patients with Polycythemia Vera (PV). We studied the relationship between splenomegaly (and its grade), thrombosis and survival in 238 patients with et and 165 patients with PV followed at our center between January 1997 and May 2019.
Keywords: splenomegaly; polycythemia vera; essential thrombocythemia splenomegaly; polycythemia vera; essential thrombocythemia

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MDPI and ACS Style

Accurso, V.; Santoro, M.; Raso, S.; Contrino, A.D.; Casimiro, P.; Di Piazza, F.; Perez, A.; Russo, A.; Siragusa, S. Splenomegaly Impacts Prognosis in Essential Thrombocythemia and Polycythemia Vera: A Single Center Study. Hematol. Rep. 2019, 11, 8281. https://doi.org/10.4081/hr.2019.8281

AMA Style

Accurso V, Santoro M, Raso S, Contrino AD, Casimiro P, Di Piazza F, Perez A, Russo A, Siragusa S. Splenomegaly Impacts Prognosis in Essential Thrombocythemia and Polycythemia Vera: A Single Center Study. Hematology Reports. 2019; 11(4):8281. https://doi.org/10.4081/hr.2019.8281

Chicago/Turabian Style

Accurso, Vincenzo, Marco Santoro, Simona Raso, Angelo Davide Contrino, Paolo Casimiro, Florinda Di Piazza, Alessandro Perez, Antonio Russo, and Sergio Siragusa. 2019. "Splenomegaly Impacts Prognosis in Essential Thrombocythemia and Polycythemia Vera: A Single Center Study" Hematology Reports 11, no. 4: 8281. https://doi.org/10.4081/hr.2019.8281

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