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Neurology International is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.

Neurol. Int., Volume 8, Issue 4 (November 2016) – 7 articles

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564 KiB  
Article
Neurological Assessment and Nerve Conduction Study Findings in 22 Patients with Alkaptonuria from Jordan
by Omar Alrawashdeh, Mohammad Alsbou, Hamed Alzoubi and Hani Al-shagahin
Neurol. Int. 2016, 8(4), 6841; https://doi.org/10.4081/ni.2016.6841 - 5 Jan 2017
Cited by 2 | Viewed by 440
Abstract
Alkaptonuria is a rare metabolic disease characterised by accumulative deposition of homogentisic acid in the connective tissue of the body. This results in early degeneration of tendons, cartilages, heart valves, and other tissues. The main objective of the study is to examine the [...] Read more.
Alkaptonuria is a rare metabolic disease characterised by accumulative deposition of homogentisic acid in the connective tissue of the body. This results in early degeneration of tendons, cartilages, heart valves, and other tissues. The main objective of the study is to examine the possibility of the nervous system involvement in patients with alkaptonuria The sample consists of two groups; 22 patients with AKU and 20 controls. A neurological assessment has been carried out including detailed medical history, neurological examination, and a nerve conduction study of the nerves of the dominant hand. The prevalence of any abnormality was compared between the two groups using chi square test. The mean values of the nerve conduction study were compared between the two groups using student t-test. There was a higher prevalence of low back pain, hearing problems and tinnitus, numbness and neuropathic pain in alkaptonuria patients. There was no significant difference between the two groups in other conditions such as seizures, headache, and syncope. The values of the nerve conduction study did not show significant difference between the two groups. Neurologically related symptoms in alkaptonuria mostly represent complications of the connective tissue degeneration rather than direct involvement of the nervous system. This has been supported further by the normal findings of the neurophysiology study in patients with alkaptonuria. Full article
722 KiB  
Case Report
Common Carotid Artery Occlusion Presenting with Recurrent Syncopal Episodes
by Imran Kader, Steven M. Jones, Catherine Harrison, Ferdinand Miteff and Senthil Kumar
Neurol. Int. 2016, 8(4), 6822; https://doi.org/10.4081/ni.2016.6822 - 5 Jan 2017
Cited by 6 | Viewed by 348
Abstract
Symptomatic common carotid artery (CCA) occlusion is an uncommon occurrence that may require surgical intervention. We aim to describe a case of CCA occlusion that presented with the unusual symptom of recurrent syncope. A 69-year-old lady presented with a history of recurrent syncopal [...] Read more.
Symptomatic common carotid artery (CCA) occlusion is an uncommon occurrence that may require surgical intervention. We aim to describe a case of CCA occlusion that presented with the unusual symptom of recurrent syncope. A 69-year-old lady presented with a history of recurrent syncopal episodes and amaurosis fugax associated with left leg weakness. She was found to have a right CCA occlusion on duplex ultrasound and angiography. She underwent a right common carotid endarterectomy and intraoperative findings revealed a heavily calcified plaque in the CCA just proximal to the bifurcation with organised thrombus filling the CCA proximally. CCA occlusion can rarely present with recurrent syncopal episodes. Surgery may be curative. Full article
553 KiB  
Case Report
Anti-Musk Positive Myasthenia Gravis and Three Semiological Cardinal Signs
by André P.C. Matta, Ana C. Andorinho F. Ferreira, Arielle Kirmse, Anna Carolina Damm, João Gabriel D.I.B. Farinhas, Mariane D. Barbosa, Mayara C.M. Teles, Camila Fiorelli, Rossano Fiorelli, Osvaldo J.M. Nascimento and Marco Orsini
Neurol. Int. 2016, 8(4), 6361; https://doi.org/10.4081/ni.2016.6361 - 5 Jan 2017
Viewed by 403
Abstract
Myasthenia gravis (MG) is a relatively uncommon disorder with an annual incidence of approximately 7 to 9 new cases per million. The prevalence is about 70 to 165 per million. The prevalence of the disease has been increasing over the past five decades. [...] Read more.
Myasthenia gravis (MG) is a relatively uncommon disorder with an annual incidence of approximately 7 to 9 new cases per million. The prevalence is about 70 to 165 per million. The prevalence of the disease has been increasing over the past five decades. This is thought to be due to better recognition of the condition, aging of the population, and the longer life span of affected patients. MG causes weakness, predominantly in bulbar, facial, and extra-ocular muscles, often fluctuating over minutes to weeks, in the absence of wasting, sensory loss, or reflex changes. The picture of fluctuating, asymmetric external ophthalmoplegia with ptosis and weak eye closure is virtually diagnostic of myasthenia. We report an atypical MG case with three semiological cardinal signs. Full article
568 KiB  
Article
Results of the Belgian Sentinel Network of General Practitioners on the Involvement of Therapists in Stroke Rehabilitation
by Silke Francois, Viviane Van Casteren, Katrien Vanthomme, Liesbeth Borgermans and Dirk Devroey
Neurol. Int. 2016, 8(4), 5846; https://doi.org/10.4081/ni.2016.5846 - 5 Jan 2017
Cited by 1 | Viewed by 363
Abstract
This study examines which therapists are involved in the rehabilitation of stroke survivors in Belgium at different points in time. A nationwide registration of stroke patients was provided by 199 and 189 family physicians working in sentinel practices for the years 2009 and [...] Read more.
This study examines which therapists are involved in the rehabilitation of stroke survivors in Belgium at different points in time. A nationwide registration of stroke patients was provided by 199 and 189 family physicians working in sentinel practices for the years 2009 and 2010 respectively. 326 patients who were diagnosed with stroke were included. Patients with paralysis/paresis received significant more physiotherapy after one month (63%) compared to non-paralysed patients (38%) (P=0.005). Residing in a nursing home was associated with higher proportions of patients receiving physiotherapy, both after one (P=0.003) and six (P=0.002) months. 31% of patients with aphasia were treated by a speech and language therapist after one month, which decreased after six months to 20%. After six months, the patients in a nursing home received significant more often speech and language therapy (P=0.004), compared to patients living at home. The proportion of patients receiving stroke rehabilitation services provided by physiotherapists, speech/language therapists and occupational therapists is rather low, especially 6 months after the critical event. Full article
537 KiB  
Article
Prevalence of Asymptomatic Neurophysiological Carpal Tunnel Syndrome in 130 Healthy Individuals
by Omar Alrawashdeh
Neurol. Int. 2016, 8(4), 6553; https://doi.org/10.4081/ni.2016.6553 - 23 Nov 2016
Cited by 7 | Viewed by 551
Abstract
Diagnosis of carpal tunnel syndrome (CTS) is frequently confirmed by performing nerve conduction studies. Previous studies demonstrated that abnormal nerve conduction study (NCS) is suggestive of CTS among asymptomatic individuals. However, previous studies included individuals with risk factors for the syndrome. A NCS [...] Read more.
Diagnosis of carpal tunnel syndrome (CTS) is frequently confirmed by performing nerve conduction studies. Previous studies demonstrated that abnormal nerve conduction study (NCS) is suggestive of CTS among asymptomatic individuals. However, previous studies included individuals with risk factors for the syndrome. A NCS was performed on the median and ulnar nerves in 130 healthy individuals. About 15% of individuals in this study demonstrated electrodiagnostic evidence of carpal tunnels syndrome. Four cases have shown signs of isolated median neuropathy with normal median sensory component. Results indicated that the most widely used method for confirming diagnosis of CTS may have up to 15% of false positives. However, most of those showed changes of minimal CTS. Isolated prolongation of the median motor latency should be investigated further as they are usually classified as moderate to severe CTS and may undergo unnecessary surgeries. Full article
622 KiB  
Review
Cervical Spondylotic Myelopathy: What the Neurologist should Know
by Celmir de Oliveira Vilaça, Marco Orsini, Marco A. Araujo Leite, Marcos R.G. de Freitas, Eduardo Davidovich, Rossano Fiorelli, Stenio Fiorelli, Camila Fiorelli, Acary Bulle Oliveira and Bruno Lima Pessoa
Neurol. Int. 2016, 8(4), 6330; https://doi.org/10.4081/ni.2016.6330 - 23 Nov 2016
Cited by 52 | Viewed by 779
Abstract
Cervical spondylotic myelopathy is a wellknown cause of disability among older people. A significant amount of these patients is asymptomatic. Once the symptoms start, the worsening may follow a progressive manner. We should suspect of spondylotic myelopathy in any individual over 55 years [...] Read more.
Cervical spondylotic myelopathy is a wellknown cause of disability among older people. A significant amount of these patients is asymptomatic. Once the symptoms start, the worsening may follow a progressive manner. We should suspect of spondylotic myelopathy in any individual over 55 years presenting progressive changes in gait or losing fine motor control of the upper limbs. Despite its frequent prevalence, this condition is still neglected and many times confused with other supratentorial lesions regarding diagnostic. Here we address some of most important aspects of this disease, calling attention to pathophysiology, the natural history, presentation, differential diagnosis, clinical assessment, and treatment. Full article
446 KiB  
Case Report
Severe Cold Lower Limbs in Patients with Parkinson’s Disease during the Summer
by Hiroshi Kataoka and Satoshi Ueno
Neurol. Int. 2016, 8(4), 6676; https://doi.org/10.4081/ni.2016.6676 - 2 Nov 2016
Cited by 4 | Viewed by 416
Abstract
Parkinson’s disease (PD) is frequently associated with vasomotor symptoms such as distal cold limbs or sensitivity to cold. Coldness of the lower limbs (COL) usually occurs in winter and is often accompanied by pain, potentially causing difficulty in walking or standing. A standard [...] Read more.
Parkinson’s disease (PD) is frequently associated with vasomotor symptoms such as distal cold limbs or sensitivity to cold. Coldness of the lower limbs (COL) usually occurs in winter and is often accompanied by pain, potentially causing difficulty in walking or standing. A standard dopaminergic treatment for such symptoms is yet to be established. We describe two patients with PD, who had severe COL during summer. For example, the patients wore many pairs of socks or used heating appliances in the summer. Severe COL can occur in summertime and can be intolerable or unpleasant, since it can worsen disability. The treatment with a dopamine agonist did not sufficiently decrease the severity of COL. Full article
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