Urea-Based Patches with Controlled Release for Potential Atopic Dermatitis Treatment
Abstract
:1. Introduction
2. Materials and Methods
2.1. Preparation of the Urea-Based Patches
2.2. Blend Electrospinning of PVB and Urea
2.3. Simultaneous Electrospinning of PVB and Electrospraying of Urea
2.4. Characterization of Urea-Based Patches
2.4.1. Membrane Morphology
2.4.2. Wetting
2.4.3. Fourier-Transform-Infrared Spectroscopy (FTIR) and Differential Scanning Calorimetry (DSC)
2.5. In Vitro Urea Release
2.6. Biocompatibility
3. Results and Discussion
3.1. Fiber Morphology
3.2. Chemical Analysis—FTIR and DSC
3.3. In Vitro Urea Release and Biocompatibility
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Krysiak, Z.J.; Stachewicz, U. Urea-Based Patches with Controlled Release for Potential Atopic Dermatitis Treatment. Pharmaceutics 2022, 14, 1494. https://doi.org/10.3390/pharmaceutics14071494
Krysiak ZJ, Stachewicz U. Urea-Based Patches with Controlled Release for Potential Atopic Dermatitis Treatment. Pharmaceutics. 2022; 14(7):1494. https://doi.org/10.3390/pharmaceutics14071494
Chicago/Turabian StyleKrysiak, Zuzanna J., and Urszula Stachewicz. 2022. "Urea-Based Patches with Controlled Release for Potential Atopic Dermatitis Treatment" Pharmaceutics 14, no. 7: 1494. https://doi.org/10.3390/pharmaceutics14071494